| Literature DB >> 1716178 |
L M Sordillo1, M J Redmond, M Campos, L Warren, L A Babiuk.
Abstract
The presence of cytokine activity in periparturient bovine mammary secretions was evaluated. Mammary secretions were modified for use in biological assays for interleukin-2 (IL-2) like and antiviral activity. The level of IL-2 like activity in mammary gland secretions was lower during the last week of gestation when compared to levels detected approximately two weeks prepartum. Antiviral titers gradually increased as parturition approached. Results from Western blots indicated that the antiviral activity observed in prepartum secretions may be due to tumor necrosis factor (TNF). Interferons (IFN) were not detected in the colostrum samples.Entities:
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Year: 1991 PMID: 1716178 PMCID: PMC1263468
Source DB: PubMed Journal: Can J Vet Res ISSN: 0830-9000 Impact factor: 1.310