Literature DB >> 2922050

Structure of tumour necrosis factor.

E Y Jones1, D I Stuart, N P Walker.   

Abstract

Tumour necrosis factor is a trimeric molecule, each subunit of which consists of an antiparallel beta-sandwich. Individual subunits from the trimer by a novel edge-to-face packing of beta-sheets. A comparison of the subunit fold with that of other proteins reveals a remarkable similarity to the 'jelly-roll' structural motif characteristic of viral coat proteins.

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Year:  1989        PMID： 2922050     DOI： 10.1038/338225a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  81 in total

1.  Anginex, a designed peptide that inhibits angiogenesis.

Authors:  A W Griffioen; D W van der Schaft; A F Barendsz-Janson; A Cox; H A Struijker Boudier; H F Hillen; K H Mayo
Journal:  Biochem J       Date:  2001-03-01       Impact factor: 3.857

2.  Thiolated recombinant human tumor necrosis factor-alpha protects against Plasmodium berghei K173-induced experimental cerebral malaria in mice.

Authors:  N S Postma; R C Hermsen; D J Crommelin; W M Eling; J Zuidema
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

3.  Construction and analysis of three-dimensional graphic model of single-chain Fv derived from an anti-human placental acidic isoferritin monoclonal antibody by computer.

Authors:  C Zhou; G Shen; H Zhu; J Yang; Y Zhang; J Feng; B Shen
Journal:  J Tongji Med Univ       Date:  2000

Review 4.  Cytokine receptors: structure and signal transduction.

Authors:  B M Foxwell; K Barrett; M Feldmann
Journal:  Clin Exp Immunol       Date:  1992-11       Impact factor: 4.330

Review 5.  Structural and functional anatomy of the globular domain of complement protein C1q.

Authors:  Uday Kishore; Rohit Ghai; Trevor J Greenhough; Annette K Shrive; Domenico M Bonifati; Mihaela G Gadjeva; Patrick Waters; Mihaela S Kojouharova; Trinad Chakraborty; Alok Agrawal
Journal:  Immunol Lett       Date:  2004-09       Impact factor: 3.685

6.  [Do antisense oligonucleotides improve viral immunopathology?].

Authors:  S Wasmuth; D Bauer; K P Steuhl; A Heiligenhaus
Journal:  Ophthalmologe       Date:  2005-03       Impact factor: 1.059

Review 7.  Quantitative structure-activity relationships (QSAR) and molecular modelling in cancer research.

Authors:  H Kubinyi
Journal:  J Cancer Res Clin Oncol       Date:  1990       Impact factor: 4.553

8.  Critical role of the C-terminus in the biological activities of human tumour necrosis factor-alpha.

Authors:  K Gase; V G Korobko; H G Wisniewski; J Le; V N Dobrynin; S A Filippov; W Gutsche; Y N Maksimova; B Schlott; L N Shingarova
Journal:  Immunology       Date:  1990-11       Impact factor: 7.397

9.  Unleashing cell death: the Fas-FADD complex.

Authors:  Sarah G Hymowitz; Vishva M Dixit
Journal:  Nat Struct Mol Biol       Date:  2010-11       Impact factor: 15.369

10.  The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.

Authors:  S Strobl; C Fernandez-Catalan; M Braun; R Huber; H Masumoto; K Nakagawa; A Irie; H Sorimachi; G Bourenkow; H Bartunik; K Suzuki; W Bode
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-18       Impact factor: 11.205
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