Literature DB >> 17147362

DNA-catalyzed transfer of a reporter group.

Tom N Grossmann1, Oliver Seitz.   

Abstract

Herein we describe a novel DNA-catalyzed transfer of a reporter group from a donating to an accepting oligo-peptide nucleic acid (PNA), generating high catalytic turnover numbers in a DNA-sequence specific manner. The demonstrated transfer of the Dabcyl group was designed to switch on emission of a fluorescein dye while switching off emission of a rhodamine dye. This setup allows the highly sensitive and selective detection of DNA-sequences in real time.

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Year:  2006        PMID： 17147362     DOI： 10.1021/ja0670097

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  25 in total

1.  Organometallic activation of a fluorogen for templated nucleic acid detection.

Authors:  Raphael M Franzini; Eric T Kool
Journal:  Org Lett       Date:  2008-06-13       Impact factor: 6.005

2.  DNA/RNA Fluorescence Imaging by Synthetic Nucleic Acids.

Authors:  Akimitsu Okamoto
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

3.  Improved templated fluorogenic probes enhance the analysis of closely related pathogenic bacteria by microscopy and flow cytometry.

Authors:  Raphael M Franzini; Eric T Kool
Journal:  Bioconjug Chem       Date:  2011-08-26       Impact factor: 4.774

4.  Two successive reactions on a DNA template: a strategy for improving background fluorescence and specificity in nucleic acid detection.

Authors:  Raphael M Franzini; Eric T Kool
Journal:  Chemistry       Date:  2011-01-10       Impact factor: 5.236

5.  Enzyme-assisted binary probe for sensitive detection of RNA and DNA.

Authors:  Yulia V Gerasimova; Sadia Peck; Dmitry M Kolpashchikov
Journal:  Chem Commun (Camb)       Date:  2010-10-21       Impact factor: 6.222

6.  Templated chemistry for sequence-specific fluorogenic detection of duplex DNA.

Authors:  Hao Li; Raphael M Franzini; Christopher Bruner; Eric T Kool
Journal:  Chembiochem       Date:  2010-10-18       Impact factor: 3.164

7.  A new usage of functionalized oligodeoxynucleotide probe for site-specific modification of a guanine base within RNA.

Authors:  Kazumitsu Onizuka; Yosuke Taniguchi; Shigeki Sasaki
Journal:  Nucleic Acids Res       Date:  2010-01-31       Impact factor: 16.971

8.  Double-stranded DNA-templated cleavage of oligonucleotides containing a P3'->N5' linkage triggered by triplex formation: the effects of chemical modifications and remarkable enhancement in reactivity.

Authors:  Kosuke Ramon Ito; Tetsuya Kodama; Masaharu Tomizu; Yoshinori Negoro; Ayako Orita; Tomohisa Osaki; Noritsugu Hosoki; Takaya Tanaka; Takeshi Imanishi; Satoshi Obika
Journal:  Nucleic Acids Res       Date:  2010-07-08       Impact factor: 16.971

9.  Efficient nucleic acid detection by templated reductive quencher release.

Authors:  Raphael M Franzini; Eric T Kool
Journal:  J Am Chem Soc       Date:  2009-11-11       Impact factor: 15.419

10.  7-Azidomethoxy-coumarins as profluorophores for templated nucleic acid detection.

Authors:  Raphael M Franzini; Eric T Kool
Journal:  Chembiochem       Date:  2008-12-15       Impact factor: 3.164
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