Literature DB >> 17113273

In vitro antidrepanocytary actvity (anti-sickle cell anemia) of some congolese plants.

P T Mpiana1, D S T Tshibangu, O M Shetonde, K N Ngbolua.   

Abstract

Thirty aqueous and ethanolic extracts from 13 congolese plants were evaluated for their antidrepanocytary activity. Twelve of these plants, Alchornea cordifolia, Afromomum albo violaceum, Annona senegalensis, Cymbopogon densiflorus, Bridelia ferruginea, Ceiba pentandra, Morinda lucida, Hymenocardia acida, Coleus kilimandcharis, Dacryodes edulis, Caloncoba welwithsii, and Vinga unguiculata exhibited significant activities, thus, supporting the claims of the traditional healers and suggesting a possible correlation between the chemical composition of these plants and their uses in traditional medicine.

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Year:  2006        PMID: 17113273     DOI: 10.1016/j.phymed.2006.05.008

Source DB:  PubMed          Journal:  Phytomedicine        ISSN: 0944-7113            Impact factor:   5.340


  18 in total

1.  Antisickling activity of butyl stearate isolated from Ocimum basilicum (Lamiaceae).

Authors:  Dorothée Dinangayi Tshilanda; Pius Tshimankinda Mpiana; Damase Nguwo Vele Onyamboko; Blaise Mavinga Mbala; Koto-Te-Nyiwa Ngbolua; Damien Sha Tshibey Tshibangu; Matthieu Kokengo Bokolo; Kalulu Muzele Taba; Teddy Kabeya Kasonga
Journal:  Asian Pac J Trop Biomed       Date:  2014-05

2.  In vitro effects of anthocyanin extracts from Justicia secunda Vahl on the solubility of haemoglobin S and membrane stability of sickle erythrocytes.

Authors:  Pius T Mpiana; KotoTe Niwa N Ngbolua; Matthieu T Bokota; Teddy K Kasonga; Emmanuel K Atibu; Damien S T Tshibangu; Virima Mudogo
Journal:  Blood Transfus       Date:  2010-10       Impact factor: 3.443

3.  In vitro antiplasmodial activity and cytotoxicity of extracts of selected medicinal plants used by traditional healers of Western cameroon.

Authors:  Denis Zofou; Mathieu Tene; Moses N Ngemenya; Pierre Tane; Vincent P K Titanji
Journal:  Malar Res Treat       Date:  2011-04-12

4.  Anti-sickling Activity of Ursolic Acid Isolated from the Leaves of Ocimum gratissimum L. (Lamiaceae).

Authors:  Dorothée Dinangayi Tshilanda; Damase NguwoVele Onyamboko; Philippe Babady-Bila; Koto-Te-Nyiwa Ngbolua; Damien ShaTshibey Tshibangu; Eddy Dia Fita Dibwe; Pius Tshimankinda Mpiana
Journal:  Nat Prod Bioprospect       Date:  2015-09-09

5.  Antifertility activity of aqueous ethanolic extract of Hymenocardia acida stem bark in female rats.

Authors:  Abu Adakole Hyacinth; Uchendu Chukwuka Nwocha
Journal:  Iran J Reprod Med       Date:  2011

6.  Evaluation of in vivo antitrypanosomal activity of crude extracts of Artemisia abyssinica against aTrypanosoma congolense isolate.

Authors:  Teka Feyera; Getachew Terefe; Workineh Shibeshi
Journal:  BMC Complement Altern Med       Date:  2014-04-01       Impact factor: 3.659

Review 7.  Phytomedicines and nutraceuticals: alternative therapeutics for sickle cell anemia.

Authors:  Ngozi Awa Imaga
Journal:  ScientificWorldJournal       Date:  2013-02-14

8.  Search for antisickling agents from plants.

Authors:  Bisnu Prasad Dash; Y Archana; Nibarana Satapathy; Soumendra Kumar Naik
Journal:  Pharmacogn Rev       Date:  2013-01

9.  New antimalarial hits from Dacryodes edulis (Burseraceae)--part I: isolation, in vitro activity, in silico "drug-likeness" and pharmacokinetic profiles.

Authors:  Denis Zofou; Esther Laure Tematio; Fidele Ntie-Kang; Mathieu Tene; Moses N Ngemenya; Pierre Tane; Vincent P K Titanji
Journal:  PLoS One       Date:  2013-11-08       Impact factor: 3.240

10.  Antisickling and toxicological evaluation of the leaves of Scoparia dulcis Linn (Scrophulariaceae).

Authors:  Tavs A Abere; Chiagozie J Okoye; Freddy O Agoreyo; Gerald I Eze; Rose I Jesuorobo; Clement O Egharevba; Pauline O Aimator
Journal:  BMC Complement Altern Med       Date:  2015-11-23       Impact factor: 3.659

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