Literature DB >> 17107759

Alpha-bulnesene, a PAF inhibitor isolated from the essential oil of Pogostemon cablin.

Ying-Chieh Tsai1, Hui-Chun Hsu, Wen-Chia Yang, Wei-Jern Tsai, Chien-Chih Chen, Takashi Watanabe.   

Abstract

Steam distilled essential oil from the aerial parts of Pogostemon cablin was analyzed by gas chromatography-mass spectrometry (GC-MS). Forty one compounds were identified of which alpha-guaiene (20.62%) and alpha-bulnesene (16.18%) were major constituents. Furthermore, fractionation of the essential oil from P. cablin guided by inhibitory activity against PAF-induced platelet aggregation led to the isolation of the sesquiterpene, alpha-bulnesene.

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Year:  2006        PMID： 17107759     DOI： 10.1016/j.fitote.2006.09.016

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  7 in total

1.  Patchouli alcohol: in vitro direct anti-influenza virus sesquiterpene in Pogostemon cablin Benth.

Authors:  Hiroaki Kiyohara; Chikara Ichino; Yuka Kawamura; Takayuki Nagai; Noriko Sato; Haruki Yamada
Journal:  J Nat Med       Date:  2011-06-14       Impact factor: 2.343

2.  Molecular Role of EGFR-MAPK Pathway in Patchouli Alcohol-Induced Apoptosis and Cell Cycle Arrest on A549 Cells In Vitro and In Vivo.

Authors:  XinGang Lu; Liu Yang; ChengHua Lu; ZhenYu Xu; HongFu Qiu; JiaJia Wu; JingWen Wang; JiaFeng Tong; Yin Zhu; Jie Shen
Journal:  Biomed Res Int       Date:  2016-10-17       Impact factor: 3.411

3.  The Complete Chloroplast Genome Sequences of the Medicinal Plant Pogostemon cablin.

Authors:  Yang He; Hongtao Xiao; Cao Deng; Liang Xiong; Jian Yang; Cheng Peng
Journal:  Int J Mol Sci       Date:  2016-06-06       Impact factor: 5.923

4.  Molecular Dynamic Screening Sesquiterpenoid Pogostemon Herba as Suggested Cyclooxygenase Inhibitor.

Authors:  Sentot Joko Raharjo; Takeshi Kikuchi
Journal:  Acta Inform Med       Date:  2016-11-01

Review 5.  Pharmacological activities and mechanisms of action of Pogostemon cablin Benth: a review.

Authors:  Chen Junren; Xie Xiaofang; Li Mengting; Xiong Qiuyun; Li Gangmin; Zhang Huiqiong; Chen Guanru; Xu Xin; Yin Yanpeng; Peng Fu; Peng Cheng
Journal:  Chin Med       Date:  2021-01-07       Impact factor: 5.455

6.  Bio-Insecticidal Nanoemulsions of Essential Oil and Lipid-Soluble Fractions of Pogostemon cablin.

Authors:  Keerthiraj Manjesh; Aditi Kundu; Anirban Dutta; Supradip Saha; Bhagyasree Sira Neelakanthaiah
Journal:  Front Plant Sci       Date:  2022-04-29       Impact factor: 5.753

7.  Survey of the genome of Pogostemon cablin provides insights into its evolutionary history and sesquiterpenoid biosynthesis.

Authors:  Yang He; Hongtao Xiao; Cao Deng; Liang Xiong; Hu Nie; Cheng Peng
Journal:  Sci Rep       Date:  2016-05-20       Impact factor: 4.379
  7 in total

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