Literature DB >> 1709734

Effects of metal ions, including Mg2+ and lanthanides, on the cleavage of ribonucleotides and RNA model compounds.

R Breslow1, D L Huang.   

Abstract

The cyclization/cleavage of 3',5'-uridyluridine to form 2',3'-cyclic uridylic acid is very effectively catalyzed by Eu3+, and the cyclization/cleavage of the 1-p-nitrophenyl phosphate ester of propane-1,2-diol also shows strong metal ion catalysis by Eu3+, Tb3+, and Yb3+. It also shows moderate catalysis by Mg2+, but not by Ca2+; Zn2+ and Pb2+ are also good catalysts. Various ligands activate these reactions further, and imidazole apparently acts as an additional base catalyst. Some cyclodextrin derivatives act to bind both the substrate and the metal ion but, contrary to what is reported elsewhere, there is no strong selectivity among nucleotides that can be ascribed to cyclodextrin binding.

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Year:  1991        PMID： 1709734      PMCID： PMC51601          DOI： 10.1073/pnas.88.10.4080

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  10 in total

1.  [Behavior and specificity of cerium and lanthanum as phosphatase models in the dephosphorylation of nucleic acids and mononucleotides].

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Journal:  Biochem Z       Date:  1954

Review 2.  Ribonuclease P: an enzyme with a catalytic RNA subunit.

Authors:  S Altman
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1989

3.  On the mechanism of action of ribonucleases: dinucleotide cleavage catalyzed by imidazole and Zn2+.

Authors:  R Breslow; D L Huang; E Anslyn
Journal:  Proc Natl Acad Sci U S A       Date:  1989-03       Impact factor: 11.205

4.  The interaction of metal ions with polynucleotides and related compounds. 13. The effect of metal ions on the enzymatic degradation of ribonucleic acid by bovine pancreatic ribonuclease and of deoxyribonucleic acid by bovine pancreatic deoxyribonuclease I.

Authors:  G L Eichhorn; P Clark; E Tarien
Journal:  J Biol Chem       Date:  1969-02-10       Impact factor: 5.157

5.  Interactions of metal ions with polynucleotides and related compounds. 3. Degradation of polyribonucleotides by lanthanum ions.

Authors:  G L Eichhorn; J J Butzow
Journal:  Biopolymers       Date:  1965       Impact factor: 2.505

6.  Probing the environment of lanthanide binding sites in yeast tRNA(Phe) by specific metal-ion-promoted cleavages.

Authors:  J Ciesiołka; T Marciniec; W Krzyzosiak
Journal:  Eur J Biochem       Date:  1989-06-15

7.  Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA.

Authors:  R S Brown; J C Dewan; A Klug
Journal:  Biochemistry       Date:  1985-08-27       Impact factor: 3.162

8.  Visualizing the higher order folding of a catalytic RNA molecule.

Authors:  D W Celander; T R Cech
Journal:  Science       Date:  1991-01-25       Impact factor: 47.728

9.  Pb(II)-catalysed cleavage of the sugar-phosphate backbone of yeast tRNAPhe--implications for lead toxicity and self-splicing RNA.

Authors:  R S Brown; B E Hingerty; J C Dewan; A Klug
Journal:  Nature       Date:  1983 Jun 9-15       Impact factor: 49.962

10.  Identification of the magnesium, europium and lead binding sites in E. coli and lupine tRNAPhe by specific metal ion-induced cleavages.

Authors:  T Marciniec; J Ciesiołka; J Wrzesinski; W J Krzyzosiak
Journal:  FEBS Lett       Date:  1989-01-30       Impact factor: 4.124
  10 in total
  21 in total

1.  Catalysis and prebiotic RNA synthesis.

Authors:  J P Ferris
Journal:  Orig Life Evol Biosph       Date:  1993-12       Impact factor: 1.950

2.  Metal ion interaction with cosubstrate in self-splicing of group I introns.

Authors:  A S Sjögren; E Pettersson; B M Sjöberg; R Strömberg
Journal:  Nucleic Acids Res       Date:  1997-02-01       Impact factor: 16.971

3.  A rapid and cost effective method in purifying small RNA.

Authors:  Marimuthu Citartan; Soo-Choon Tan; Thean-Hock Tang
Journal:  World J Microbiol Biotechnol       Date:  2011-06-03       Impact factor: 3.312

4.  Deoxypolypeptides bind and cleave RNA.

Authors:  Liang Cheng; Adaickapillai Mahendran; Ruben L Gonzalez; Ronald Breslow
Journal:  Proc Natl Acad Sci U S A       Date:  2014-05-19       Impact factor: 11.205

5.  A catalytic carbohydrate contributes to bacterial antibiotic resistance.

Authors:  Paul de Figueiredo; Becky Terra; Jasbir Kaur Anand; Toshiyuki Hikita; Martin Sadilek; Dave E Monks; Anastasiya Lenskiy; Senitiroh Hakomori; Eugene W Nester
Journal:  Extremophiles       Date:  2006-10-18       Impact factor: 2.395

6.  Binding and biomimetic cleavage of the RNA poly(U) by synthetic polyimidazoles.

Authors:  Liang Cheng; K G Abhilash; Ronald Breslow
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-23       Impact factor: 11.205

7.  Isotope effect analyses provide evidence for an altered transition state for RNA 2'-O-transphosphorylation catalyzed by Zn(2+).

Authors:  Shuming Zhang; Hong Gu; Haoyuan Chen; Emily Strong; Edward W Ollie; Daniel Kellerman; Danni Liang; Masaru Miyagi; Vernon E Anderson; Joseph A Piccirilli; Darrin M York; Michael E Harris
Journal:  Chem Commun (Camb)       Date:  2016-03-25       Impact factor: 6.222

8.  Self-assembled gold nanocrystal micelles act as an excellent artificial nanozyme with ribonuclease activity.

Authors:  Zhiming Zhang; Qiuan Fu; Xiangqiu Li; Xin Huang; Jiayun Xu; Jiacong Shen; Junqiu Liu
Journal:  J Biol Inorg Chem       Date:  2009-02-21       Impact factor: 3.358

9.  Selective cleavage of pyrophosphate linkages.

Authors:  J Visscher; A W Schwartz
Journal:  Nucleic Acids Res       Date:  1992-11-11       Impact factor: 16.971

10.  Design of peptide-acridine mimics of ribonuclease activity.

Authors:  C H Tung; Z Wei; M J Leibowitz; S Stein
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-01       Impact factor: 11.205
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