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Literature DB >> 17088477

Aph(3')-IIc, an aminoglycoside resistance determinant from Stenotrophomonas maltophilia.

Abstract

We report the characterization of an intrinsic, chromosomally carried aph(3')-IIc gene from Stenotrophomonas maltophilia clinical isolate K279a, encoding an aminoglycoside phosphotransferase enzyme that significantly increases MICs of kanamycin, neomycin, butirosin, and paromomycin when expressed in Escherichia coli. Disruption of aph(3')-IIc in K279a results in decreased MICs of these drugs.

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Year: 2006 PMID： 17088477 PMCID： PMC1797691 DOI： 10.1128/AAC.00795-06

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

13 in total

1. Plasmid location and molecular heterogeneity of the L1 and L2 beta-lactamase genes of Stenotrophomonas maltophilia.

Authors: M B Avison; C S Higgins; C J von Heldreich; P M Bennett; T R Walsh
Journal: Antimicrob Agents Chemother Date: 2001-02 Impact factor: 5.191

2. Basic local alignment search tool.

Authors: S F Altschul; W Gish; W Miller; E W Myers; D J Lipman
Journal: J Mol Biol Date: 1990-10-05 Impact factor: 5.469

3. Characterization of the chromosomal aac(6')-Iz gene of Stenotrophomonas maltophilia.

Authors: T Lambert; M C Ploy; F Denis; P Courvalin
Journal: Antimicrob Agents Chemother Date: 1999-10 Impact factor: 5.191

4. Nucleotide sequence of the kanamycin resistance transposon Tn903.

Authors: A Oka; H Sugisaki; M Takanami
Journal: J Mol Biol Date: 1981-04-05 Impact factor: 5.469

5. Nucleotide sequence and exact localization of the neomycin phosphotransferase gene from transposon Tn5.

Authors: E Beck; G Ludwig; E A Auerswald; B Reiss; H Schaller
Journal: Gene Date: 1982-10 Impact factor: 3.688

6. Differential regulation of L1 and L2 beta-lactamase expression in Stenotrophomonas maltophilia.

Authors: Matthew B Avison; Catherine S Higgins; Peter J Ford; Charlotte J von Heldreich; Timothy R Walsh; Peter M Bennett
Journal: J Antimicrob Chemother Date: 2002-02 Impact factor: 5.790

7. Beta-lactam resistance and beta-lactamase expression in clinical Stenotrophomonas maltophilia isolates having defined phylogenetic relationships.

Authors: Virginia C Gould; Aki Okazaki; Matthew B Avison
Journal: J Antimicrob Chemother Date: 2005-12-13 Impact factor: 5.790

8. Sequence and characterization of a novel chromosomal aminoglycoside phosphotransferase gene, aph (3')-IIb, in Pseudomonas aeruginosa.

Authors: H Hächler; P Santanam; F H Kayser
Journal: Antimicrob Agents Chemother Date: 1996-05 Impact factor: 5.191

9. Role of the acetyltransferase AAC(6')-Iz modifying enzyme in aminoglycoside resistance in Stenotrophomonas maltophilia.

Authors: Xian-Zhi Li; Li Zhang; Geoffrey A McKay; Keith Poole
Journal: J Antimicrob Chemother Date: 2003-03-13 Impact factor: 5.790

10. A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants.

Authors: T T Hoang; R R Karkhoff-Schweizer; A J Kutchma; H P Schweizer
Journal: Gene Date: 1998-05-28 Impact factor: 3.688

31 in total

1. Induction of L1 and L2 beta-lactamase production in Stenotrophomonas maltophilia is dependent on an AmpR-type regulator.

Authors: Aki Okazaki; Matthew B Avison
Journal: Antimicrob Agents Chemother Date: 2008-01-22 Impact factor: 5.191

2. Overexpression of SmeDEF Efflux Pump Decreases Aminoglycoside Resistance in Stenotrophomonas maltophilia.

Authors: Yi-Wei Huang; Cheng-Wen Lin; Hsiao-Chen Ning; Yi-Tsung Lin; Yi-Chih Chang; Tsuey-Ching Yang
Journal: Antimicrob Agents Chemother Date: 2017-04-24 Impact factor: 5.191

3. Coordinate hyperproduction of SmeZ and SmeJK efflux pumps extends drug resistance in Stenotrophomonas maltophilia.

Authors: Virginia C Gould; Aki Okazaki; Matthew B Avison
Journal: Antimicrob Agents Chemother Date: 2012-11-12 Impact factor: 5.191

Review 4. Aminoglycoside modifying enzymes.

Authors: Maria S Ramirez; Marcelo E Tolmasky
Journal: Drug Resist Updat Date: 2010-09-15 Impact factor: 18.500

5. Stenotrophomonas maltophilia strains replicate and persist in the murine lung, but to significantly different degrees.

Authors: Ruella Rouf; Sara M Karaba; Jenny Dao; Nicholas P Cianciotto
Journal: Microbiology (Reading) Date: 2011-05-05 Impact factor: 2.777

6. Inactivation of Lytic Transglycosylases Increases Susceptibility to Aminoglycosides and Macrolides by Altering the Outer Membrane Permeability of Stenotrophomonas maltophilia.

Authors: Chao-Jung Wu; Yi-Wei Huang; Yi-Tsung Lin; Tsuey-Ching Yang
Journal: Antimicrob Agents Chemother Date: 2016-04-22 Impact factor: 5.191

7. Polymorphic mutation frequencies of clinical and environmental Stenotrophomonas maltophilia populations.

Authors: María Carmen Turrientes; María Rosario Baquero; María Blanca Sánchez; Sylvia Valdezate; Esther Escudero; Gabrielle Berg; Rafael Cantón; Fernando Baquero; Juan Carlos Galán; José Luis Martínez
Journal: Appl Environ Microbiol Date: 2010-01-22 Impact factor: 4.792

8. Diffusible signal factor-dependent cell-cell signaling and virulence in the nosocomial pathogen Stenotrophomonas maltophilia.

Authors: Yvonne Fouhy; Karl Scanlon; Katherine Schouest; Charles Spillane; Lisa Crossman; Matthew B Avison; Robert P Ryan; J Maxwell Dow
Journal: J Bacteriol Date: 2007-04-27 Impact factor: 3.490

9. New aminoglycoside-modifying enzymes APH(3')-VIII and APH(3')-IX in Acinetobacter rudis and Acinetobacter gerneri.

Authors: Eun-Jeong Yoon; Catherine Grillot-Courvalin; Patrice Courvalin
Journal: J Antibiot (Tokyo) Date: 2016-12-14 Impact factor: 2.649

10. Mutations in Ribosomal Protein RplA or Treatment with Ribosomal Acting Antibiotics Activates Production of Aminoglycoside Efflux Pump SmeYZ in Stenotrophomonas maltophilia.

Authors: Karina Calvopiña; Punyawee Dulyayangkul; Matthew B Avison
Journal: Antimicrob Agents Chemother Date: 2020-01-27 Impact factor: 5.191