Literature DB >> 17074422

Synthesis of some bioactive 2-bromo-5-methoxy-N'-[4-(aryl)-1,3-thiazol-2-yl]benzohydrazide derivatives.

K K Vijaya Raj1, B Narayana, B V Ashalatha, N Suchetha Kumari, B K Sarojini.   

Abstract

Eight novel 2-bromo-5-methoxy-N'-[4-(aryl)-1,3-thiazol-2-yl]benzohydrazide derivatives were prepared and characterized by analytical and spectral analyses. All the compounds were screened for their analgesic, antifungal and antibacterial activities and three of the compounds were screened for antiproliferative activity. Two of the newly synthesized compounds exhibited promising analgesic activity and one compound exhibited in vitro antiproliferative activity.

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Year:  2006        PMID: 17074422     DOI: 10.1016/j.ejmech.2006.09.010

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  31 in total

1.  (E)-4-Hydr-oxy-N'-(4-nitro-benzyl-idene)benzohydrazide.

Authors:  Cong-Ming Li; Hong-Yan Ban
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-06-06

2.  (E)-N'-(5-Bromo-2-methoxy-benzyl-idene)-3-methoxy-benzohydrazide.

Authors:  Cong-Ming Li; Hong-Yan Ban
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-03-28

3.  (E)-N'-(5-Bromo-2-methoxy-benzyl-idene)-4-methoxy-benzohydrazide.

Authors:  Hong-Yan Ban; Cong-Ming Li
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-11-08

4.  (E)-2-Meth-oxy-N'-(4-nitro-benzyl-idene)benzohydrazide.

Authors:  Hong-Yan Ban; Cong-Ming Li
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-11-28

5.  (E)-N'-(2-Chloro-5-nitro-benzyl-idene)-4-methoxy-benzohydrazide.

Authors:  Hong-Yan Ban; Cong-Ming Li
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-10-25

6.  Synthesis and Antinociceptive Effect of Some Thiazole-Piperazine Derivatives: Involvement of Opioidergic System in the Activity.

Authors:  Nazlı Turan Yücel; Derya Osmaniye; Ümmühan Kandemir; Asaf Evrim Evren; Özgür Devrim Can; Ümide Demir Özkay
Journal:  Molecules       Date:  2021-06-02       Impact factor: 4.411

7.  N'-(3-Bromo-5-chloro-2-hy-droxy-benzyl-idene)-2H-1,3-benzodioxole-5-carbo-hydrazide.

Authors:  Jiao Wei; Hong-Yan Ban; Xiao-Zhi Sun
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-04-06

8.  (E)-4-Meth-oxy-N'-(4-nitro-benzyl-idene)benzohydrazide methanol monosolvate.

Authors:  Hong-Yan Ban
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-11-20

9.  (E)-N'-(5-Bromo-2-hy-droxy-benzyl-idene)-2-meth-oxy-benzohydrazide.

Authors:  Shi-Yong Liu; Zhonglu You
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-06-16

10.  (E)-N'-[4-(Dimethyl-amino)-benzyl-idene]-2-meth-oxy-benzohydrazide.

Authors:  Shi-Yong Liu; Xiaoling Wang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-06-26
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