Literature DB >> 17057847

Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc-imidazole hybrid inhibitor.

Bhagavathy Shanmugasundaram1, Aleksandra W Debowski, Rebecca J Dennis, Gideon J Davies, David J Vocadlo, Andrea Vasella.   

Abstract

Synthesis of a PUGNAc-imidazole hybrid and its characterization as an inhibitor of human O-GlcNAcase through enzyme kinetics and X-ray structural analysis.

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Year:  2006        PMID： 17057847     DOI： 10.1039/b612154c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  19 in total

1.  Detection and analysis of proteins modified by O-linked N-acetylglucosamine.

Authors:  Natasha E Zachara; Keith Vosseller; Gerald W Hart
Journal:  Curr Protoc Protein Sci       Date:  2011-11

Review 2.  The roles of O-linked β-N-acetylglucosamine in cardiovascular physiology and disease.

Authors:  Natasha E Zachara
Journal:  Am J Physiol Heart Circ Physiol       Date:  2012-01-27       Impact factor: 4.733

3.  Protein O-GlcNAcylation: A critical regulator of the cellular response to stress.

Authors:  John C Chatham; Richard B Marchase
Journal:  Curr Signal Transduct Ther       Date:  2010-01

Review 4.  Chemical approaches to understanding O-GlcNAc glycosylation in the brain.

Authors:  Jessica E Rexach; Peter M Clark; Linda C Hsieh-Wilson
Journal:  Nat Chem Biol       Date:  2008-02       Impact factor: 15.040

5.  Detection and analysis of proteins modified by O-linked N-acetylglucosamine.

Authors:  Natasha E Zachara; Keith Vosseller; Gerald W Hart
Journal:  Curr Protoc Mol Biol       Date:  2011-07

6.  Mechanism, Structure, and Inhibition of O-GlcNAc Processing Enzymes.

Authors:  Tracey M Gloster; David J Vocadlo
Journal:  Curr Signal Transduct Ther       Date:  2010-01

Review 7.  O-GlcNAc and the cardiovascular system.

Authors:  Sujith Dassanayaka; Steven P Jones
Journal:  Pharmacol Ther       Date:  2013-11-25       Impact factor: 12.310

Review 8.  The role of protein O-linked beta-N-acetylglucosamine in mediating cardiac stress responses.

Authors:  John C Chatham; Richard B Marchase
Journal:  Biochim Biophys Acta       Date:  2009-07-14

Review 9.  Glycosidase inhibition: assessing mimicry of the transition state.

Authors:  Tracey M Gloster; Gideon J Davies
Journal:  Org Biomol Chem       Date:  2009-11-05       Impact factor: 3.876

Review 10.  Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity.

Authors:  Ronald J Copeland; John W Bullen; Gerald W Hart
Journal:  Am J Physiol Endocrinol Metab       Date:  2008-04-29       Impact factor: 4.310
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