Literature DB >> 17055428

Keeping transcriptional activators under control.

Thomas Kodadek1, Devanjan Sikder, Kip Nalley.   

Abstract

Transcriptional activators need to be modulated and eventually switched off after the initial event that triggers their activation. Here, we discuss how ubiquitination of activators and their proteasome-mediated turnover are crucial steps in this process.

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Year:  2006        PMID: 17055428     DOI: 10.1016/j.cell.2006.10.002

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  50 in total

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3.  The role of the proteasomal ATPases and activator monoubiquitylation in regulating Gal4 binding to promoters.

Authors:  Anwarul Ferdous; Devanjan Sikder; Thomas Gillette; Kip Nalley; Thomas Kodadek; Stephen Albert Johnston
Journal:  Genes Dev       Date:  2006-12-13       Impact factor: 11.361

4.  Circadian activity and abundance rhythms of the Neurospora clock transcription factor WCC associated with rapid nucleo-cytoplasmic shuttling.

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5.  Posttranslational regulation of NF-YA modulates NF-Y transcriptional activity.

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Review 6.  No Splicing, no dicing: non-proteolytic roles of the ubiquitin-proteasome system in transcription.

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Journal:  J Biol Chem       Date:  2009-12-02       Impact factor: 5.157

7.  Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator.promoter complex by the proteasomal ATPases.

Authors:  Young-Chan Kim; Shwu-Yuan Wu; Hyun-Suk Lim; Cheng-Ming Chiang; Thomas Kodadek
Journal:  J Biol Chem       Date:  2009-10-21       Impact factor: 5.157

8.  The 19 s proteasome subcomplex establishes a specific protein interaction network at the promoter for stimulated transcriptional initiation in vivo.

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Journal:  J Biol Chem       Date:  2009-12-18       Impact factor: 5.157

9.  Evolutionary divergence of the sex-determining gene MID uncoupled from the transition to anisogamy in volvocine algae.

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Journal:  Development       Date:  2018-04-09       Impact factor: 6.868

Review 10.  Emerging roles for chromatin as a signal integration and storage platform.

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Journal:  Nat Rev Mol Cell Biol       Date:  2013-04       Impact factor: 94.444

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