| Literature DB >> 17055428 |
Thomas Kodadek1, Devanjan Sikder, Kip Nalley.
Abstract
Transcriptional activators need to be modulated and eventually switched off after the initial event that triggers their activation. Here, we discuss how ubiquitination of activators and their proteasome-mediated turnover are crucial steps in this process.Mesh:
Substances:
Year: 2006 PMID: 17055428 DOI: 10.1016/j.cell.2006.10.002
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582