Literature DB >> 17048091

Abnormalities on the neurological examination and EEG in young children with pervasive developmental disorders.

Natacha Akshoomoff1, Nikdokht Farid, Eric Courchesne, Richard Haas.   

Abstract

This study examined the nature and frequency of neurological and EEG abnormalities in 60 young children (ages 2-6 years) with pervasive developmental disorders. A number of standard neurological functions could not be adequately assessed due to the young age of the children and/or limited comprehension and cooperation. The most common neurological deficits were hyporeflexia, stereotypies, and hypotonia. EEG abnormalities were identified in 32% of the children while only two children were known to have clinical seizures. The frequency of cases with hypotonia or hyporeflexia was more common than in older children with this diagnosis. Results also indicate that EEG abnormalities are common in this young population but clinical seizures are rare, confirming other studies.

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Year:  2007        PMID: 17048091      PMCID: PMC2094050          DOI: 10.1007/s10803-006-0216-9

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN: 0162-3257


  27 in total

1.  Neurologic abnormalities in infantile autism.

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2.  Underdevelopment of the postural control system in autism.

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Review 4.  Epilepsy and epileptiform EEG: association with autism and language disorders.

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Journal:  Ment Retard Dev Disabil Res Rev       Date:  2000

5.  Atypical patterns of cerebral motor activation in autism: a functional magnetic resonance study.

Authors:  R A Müller; K Pierce; J B Ambrose; G Allen; E Courchesne
Journal:  Biol Psychiatry       Date:  2001-04-15       Impact factor: 13.382

6.  The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism.

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Authors:  R F Tuchman; I Rapin
Journal:  Pediatrics       Date:  1997-04       Impact factor: 7.124

8.  EEG features and epilepsy in patients with autism.

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Journal:  Brain Dev       Date:  1995 May-Jun       Impact factor: 1.961

9.  Movement analysis in infancy may be useful for early diagnosis of autism.

Authors:  P Teitelbaum; O Teitelbaum; J Nye; J Fryman; R G Maurer
Journal:  Proc Natl Acad Sci U S A       Date:  1998-11-10       Impact factor: 11.205

Review 10.  Current topic: Screening and surveillance for autism and pervasive developmental disorders.

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Journal:  Arch Dis Child       Date:  2001-06       Impact factor: 3.791

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  9 in total

Review 1.  Epilepsy and Autism.

Authors:  Ashura W Buckley; Gregory L Holmes
Journal:  Cold Spring Harb Perspect Med       Date:  2016-04-01       Impact factor: 6.915

Review 2.  The role of epilepsy and epileptiform EEGs in autism spectrum disorders.

Authors:  Sarah J Spence; Mark T Schneider
Journal:  Pediatr Res       Date:  2009-06       Impact factor: 3.756

3.  An investigation of sleep characteristics, EEG abnormalities and epilepsy in developmentally regressed and non-regressed children with autism.

Authors:  Flavia Giannotti; Flavia Cortesi; Antonella Cerquiglini; Daniela Miraglia; Cristina Vagnoni; Teresa Sebastiani; Paola Bernabei
Journal:  J Autism Dev Disord       Date:  2008-05-16

Review 4.  Experimental Therapeutic Strategies in Epilepsies Using Anti-Seizure Medications.

Authors:  Fakher Rahim; Reza Azizimalamiri; Mehdi Sayyah; Alireza Malayeri
Journal:  J Exp Pharmacol       Date:  2021-03-11

5.  Two-Year Follow-up of Isolated Epileptiform Discharges in Autism: An Endophenotypic Biomarker?

Authors:  Vimal Doshi Veerappan; B Sweetha; H R Kavitha; D Sivalingam; Shanthi Nambi; Leema Pauline
Journal:  Indian J Psychol Med       Date:  2018 May-Jun

Review 6.  Electroencephalographic Abnormalities in Autism Spectrum Disorder: Characteristics and Therapeutic Implications.

Authors:  Francesco Precenzano; Lucia Parisi; Valentina Lanzara; Luigi Vetri; Francesca Felicia Operto; Grazia Maria Giovanna Pastorino; Maria Ruberto; Giovanni Messina; Maria Cristina Risoleo; Claudia Santoro; Ilaria Bitetti; Rosa Marotta
Journal:  Medicina (Kaunas)       Date:  2020-08-19       Impact factor: 2.430

Review 7.  Inhibiting Epileptiform Activity in Cognitive Disorders: Possibilities for a Novel Therapeutic Approach.

Authors:  Andras Attila Horvath; Emoke Anna Csernus; Sara Lality; Rafal M Kaminski; Anita Kamondi
Journal:  Front Neurosci       Date:  2020-10-15       Impact factor: 4.677

8.  Patterns of Restricted and Repetitive Behaviors in Autism Spectrum Disorders: A Cross-Sectional Video Recording Study. Preliminary Report.

Authors:  Enzo Grossi; Elisa Caminada; Michela Goffredo; Beatrice Vescovo; Tristana Castrignano; Daniele Piscitelli; Giulio Valagussa; Marco Franceschini; Franco Vanzulli
Journal:  Brain Sci       Date:  2021-05-21

9.  Minor Neurological Dysfunctions (MNDs) in Autistic Children without Intellectual Disability.

Authors:  Gabriele Tripi; Sylvie Roux; Marco Carotenuto; Frédérique Bonnet-Brilhault; Michele Roccella
Journal:  J Clin Med       Date:  2018-04-12       Impact factor: 4.241

  9 in total

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