Literature DB >> 17042780

Diversity of human U2AF splicing factors.

Inês Mollet1, Nuno L Barbosa-Morais, Jorge Andrade, Maria Carmo-Fonseca.   

Abstract

U2 snRNP auxiliary factor (U2AF) is an essential heterodimeric splicing factor composed of two subunits, U2AF(65) and U2AF(35). During the past few years, a number of proteins related to both U2AF(65) and U2AF(35) have been discovered. Here, we review the conserved structural features that characterize the U2AF protein families and their evolutionary emergence. We perform a comprehensive database search designed to identify U2AF protein isoforms produced by alternative splicing, and we discuss the potential implications of U2AF protein diversity for splicing regulation.

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Year:  2006        PMID: 17042780     DOI: 10.1111/j.1742-4658.2006.05502.x

Source DB:  PubMed          Journal:  FEBS J        ISSN: 1742-464X            Impact factor:   5.542


  22 in total

Review 1.  Diverse regulation of 3' splice site usage.

Authors:  Muhammad Sohail; Jiuyong Xie
Journal:  Cell Mol Life Sci       Date:  2015-09-14       Impact factor: 9.261

2.  Genomic functions of U2AF in constitutive and regulated splicing.

Authors:  Tongbin Wu; Xiang-Dong Fu
Journal:  RNA Biol       Date:  2015       Impact factor: 4.652

3.  UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex.

Authors:  Galina A Stepanyuk; Pedro Serrano; Eigen Peralta; Carol L Farr; Herbert L Axelrod; Michael Geralt; Debanu Das; Hsiu-Ju Chiu; Lukasz Jaroszewski; Ashley M Deacon; Scott A Lesley; Marc-André Elsliger; Adam Godzik; Ian A Wilson; Kurt Wüthrich; Daniel R Salomon; James R Williamson
Journal:  Acta Crystallogr D Struct Biol       Date:  2016-03-24       Impact factor: 7.652

4.  A large-scale functional screen identifies Nova1 and Ncoa3 as regulators of neuronal miRNA function.

Authors:  Peter H Störchel; Juliane Thümmler; Gabriele Siegel; Ayla Aksoy-Aksel; Federico Zampa; Simon Sumer; Gerhard Schratt
Journal:  EMBO J       Date:  2015-06-23       Impact factor: 11.598

Review 5.  Structural and functional modularity of the U2 snRNP in pre-mRNA splicing.

Authors:  Clarisse van der Feltz; Aaron A Hoskins
Journal:  Crit Rev Biochem Mol Biol       Date:  2019-11-20       Impact factor: 8.250

6.  Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36.

Authors:  Sérgio Fernandes de Almeida; Ana Rita Grosso; Frederic Koch; Romain Fenouil; Sílvia Carvalho; Jorge Andrade; Helena Levezinho; Marta Gut; Dirk Eick; Ivo Gut; Jean-Christophe Andrau; Pierre Ferrier; Maria Carmo-Fonseca
Journal:  Nat Struct Mol Biol       Date:  2011-07-26       Impact factor: 15.369

7.  Roles of polypyrimidine tract binding proteins in major immediate-early gene expression and viral replication of human cytomegalovirus.

Authors:  Ruth S Cruz Cosme; Yasuhiro Yamamura; Qiyi Tang
Journal:  J Virol       Date:  2009-01-14       Impact factor: 5.103

8.  Control of alternative splicing by signal-dependent degradation of splicing-regulatory proteins.

Authors:  Rebeccah J Katzenberger; Matthew S Marengo; David A Wassarman
Journal:  J Biol Chem       Date:  2009-02-13       Impact factor: 5.157

9.  Unconstrained mining of transcript data reveals increased alternative splicing complexity in the human transcriptome.

Authors:  I G Mollet; Claudia Ben-Dov; Daniel Felício-Silva; A R Grosso; Pedro Eleutério; Ruben Alves; Ray Staller; Tito Santos Silva; Maria Carmo-Fonseca
Journal:  Nucleic Acids Res       Date:  2010-04-12       Impact factor: 16.971

Review 10.  The impact of alternative splicing in vivo: mouse models show the way.

Authors:  Tarik Möröy; Florian Heyd
Journal:  RNA       Date:  2007-06-11       Impact factor: 4.942

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