Literature DB >> 17031791

Orbitrap mass analyzer--overview and applications in proteomics.

Michaela Scigelova1, Alexander Makarov.   

Abstract

The orbitrap mass analyzer is proving itself as a useful addition to a proteomics tool box. The key attributes of this analyzer are accurate mass and high resolution similar to those achievable with FT ICR instrumentation. The basic principles underlying these capabilities, and how they translate into benefits in real-life proteomics experiments are discussed. The focus is on reviewing examples of protein identification with bottom-up and top-down approaches, and detection of post-translational modifications.

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Year:  2006        PMID： 17031791     DOI： 10.1002/pmic.200600528

Source DB:  PubMed          Journal:  Proteomics        ISSN： 1615-9853            Impact factor:   3.984


  53 in total

1.  Megadalton complexes in the chloroplast stroma of Arabidopsis thaliana characterized by size exclusion chromatography, mass spectrometry, and hierarchical clustering.

Authors:  Paul Dominic B Olinares; Lalit Ponnala; Klaas J van Wijk
Journal:  Mol Cell Proteomics       Date:  2010-04-26       Impact factor: 5.911

2.  Large-scale label-free quantitative proteomics of the pea aphid-Buchnera symbiosis.

Authors:  Anton Poliakov; Calum W Russell; Lalit Ponnala; Harold J Hoops; Qi Sun; Angela E Douglas; Klaas J van Wijk
Journal:  Mol Cell Proteomics       Date:  2011-03-18       Impact factor: 5.911

3.  Discovery of mouse spleen signaling responses to anthrax using label-free quantitative phosphoproteomics via mass spectrometry.

Authors:  Nathan P Manes; Li Dong; Weidong Zhou; Xiuxia Du; Nikitha Reghu; Arjan C Kool; Dahan Choi; Charles L Bailey; Emanuel F Petricoin; Lance A Liotta; Serguei G Popov
Journal:  Mol Cell Proteomics       Date:  2010-12-28       Impact factor: 5.911

Review 4.  Decoding protein modifications using top-down mass spectrometry.

Authors:  Nertila Siuti; Neil L Kelleher
Journal:  Nat Methods       Date:  2007-10       Impact factor: 28.547

5.  Anion and cation mixed-bed ion exchange for enhanced multidimensional separations of peptides and phosphopeptides.

Authors:  Akira Motoyama; Tao Xu; Cristian I Ruse; James A Wohlschlegel; John R Yates
Journal:  Anal Chem       Date:  2007-04-06       Impact factor: 6.986

6.  Reading the metabolic fine print. The application of metabolomics to diagnostics, drug research and nutrition might be integral to improved health and personalized medicine.

Authors:  Philip Hunter
Journal:  EMBO Rep       Date:  2009-01       Impact factor: 8.807

7.  Rephasing ion packets in the Orbitrap mass analyzer to improve resolution and peak shape.

Authors:  Richard H Perry; Qizhi Hu; Gary A Salazar; R Graham Cooks; Robert J Noll
Journal:  J Am Soc Mass Spectrom       Date:  2009-02-12       Impact factor: 3.109

8.  Periodic patterns in distributions of peptide masses.

Authors:  Shane L Hubler; Gheorghe Craciun
Journal:  Biosystems       Date:  2012-05-08       Impact factor: 1.973

9.  Screening for EphB signaling effectors using SILAC with a linear ion trap-orbitrap mass spectrometer.

Authors:  Guoan Zhang; David Fenyö; Thomas A Neubert
Journal:  J Proteome Res       Date:  2008-09-25       Impact factor: 4.466

Review 10.  Exploring Oxidative Reactions in Hemoglobin Variants Using Mass Spectrometry: Lessons for Engineering Oxidatively Stable Oxygen Therapeutics.

Authors:  Michael Brad Strader; Abdu I Alayash
Journal:  Antioxid Redox Signal       Date:  2016-10-20       Impact factor: 8.401
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