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Literature DB >> 17030567

Signature-tagged transposon mutagenesis identifies novel Mycobacterium tuberculosis genes involved in the parasitism of human macrophages.

Vania Rosas-Magallanes¹, Gustavo Stadthagen-Gomez, Jean Rauzier, Luis B Barreiro, Ludovic Tailleux, Frédéric Boudou, Ruth Griffin, Jérome Nigou, Mary Jackson, Brigitte Gicquel, Olivier Neyrolles.

Abstract

Using signature-tagged transposon mutagenesis, we isolated 23 Mycobacterium tuberculosis mutants, corresponding to 21 genes or genetic regions, attenuated in their ability to parasitize human macrophages. Mutants disrupted in the ABC transporter-encoding genes Rv0986 and Rv0987 were further characterized as being impaired in their ability to bind to host cells.

Entities: Disease Species

Mesh：

Substances：

Year: 2006 PMID： 17030567 PMCID： PMC1828433 DOI： 10.1128/IAI.00058-06

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

31 in total

1. Search for genes potentially involved in Mycobacterium tuberculosis virulence by mRNA differential display.

Authors: L Rindi; N Lari; C Garzelli
Journal: Biochem Biophys Res Commun Date: 1999-04-29 Impact factor: 3.575

2. Survival of mice infected with Mycobacterium smegmatis containing large DNA fragments from Mycobacterium tuberculosis.

Authors: F C Bange; F M Collins; W R Jacobs
Journal: Tuber Lung Dis Date: 1999

Review 3. How can immunology contribute to the control of tuberculosis?

Authors: S H Kaufmann
Journal: Nat Rev Immunol Date: 2001-10 Impact factor: 53.106

4. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling.

Authors: D Mitra; B Saha; D Das; H G Wiker; A K Das
Journal: Tuberculosis (Edinb) Date: 2005-10-26 Impact factor: 3.131

5. Identification of Mycobacterium tuberculosis RNAs synthesized in response to phagocytosis by human macrophages by selective capture of transcribed sequences (SCOTS).

Authors: J E Graham; J E Clark-Curtiss
Journal: Proc Natl Acad Sci U S A Date: 1999-09-28 Impact factor: 11.205

6. Mycobacterium tuberculosis genes induced during infection of human macrophages.

Authors: Eugenie Dubnau; Patricia Fontán; Riccardo Manganelli; Sonia Soares-Appel; Issar Smith
Journal: Infect Immun Date: 2002-06 Impact factor: 3.441

7. Constrained intracellular survival of Mycobacterium tuberculosis in human dendritic cells.

Authors: Ludovic Tailleux; Olivier Neyrolles; Stéphanie Honoré-Bouakline; Emmanuelle Perret; Françoise Sanchez; Jean-Pierre Abastado; Philippe Henri Lagrange; Jean Claude Gluckman; Michelle Rosenzwajg; Jean-Louis Herrmann
Journal: J Immunol Date: 2003-02-15 Impact factor: 5.422

8. Genetic requirements for mycobacterial survival during infection.

Authors: Christopher M Sassetti; Eric J Rubin
Journal: Proc Natl Acad Sci U S A Date: 2003-10-20 Impact factor: 11.205

9. Attenuation of virulence by disruption of the Mycobacterium tuberculosis erp gene.

Authors: F X Berthet; M Lagranderie; P Gounon; C Laurent-Winter; D Ensergueix; P Chavarot; F Thouron; E Maranghi; V Pelicic; D Portnoï; G Marchal; B Gicquel
Journal: Science Date: 1998-10-23 Impact factor: 47.728

10. Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment.

Authors: Dirk Schnappinger; Sabine Ehrt; Martin I Voskuil; Yang Liu; Joseph A Mangan; Irene M Monahan; Gregory Dolganov; Brad Efron; Philip D Butcher; Carl Nathan; Gary K Schoolnik
Journal: J Exp Med Date: 2003-09-01 Impact factor: 14.307

30 in total

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Authors: Monique J Williams; Bavesh D Kana; Valerie Mizrahi
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Review 2. Signature tagged mutagenesis in the functional genetic analysis of gastrointestinal pathogens.

Authors: Joanne Cummins; Cormac G M Gahan
Journal: Gut Microbes Date: 2012-03-01

3. bis-Molybdopterin guanine dinucleotide is required for persistence of Mycobacterium tuberculosis in guinea pigs.

Authors: Monique J Williams; Crystal A Shanley; Andrew Zilavy; Blas Peixoto; Claudia Manca; Gilla Kaplan; Ian M Orme; Valerie Mizrahi; Bavesh D Kana
Journal: Infect Immun Date: 2014-11-17 Impact factor: 3.441

4. Cloning, overexpression, purification, crystallization and preliminary X-ray analysis of 3-ketosteroid Δ(4)-(5α)-dehydrogenase from Rhodococcus jostii RHA1.

Authors: Niels van Oosterwijk; Jan Knol; Lubbert Dijkhuizen; Robert van der Geize; Bauke W Dijkstra
Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun Date: 2011-09-30

5. The actinobacterial mce4 locus encodes a steroid transporter.

Authors: William W Mohn; Robert van der Geize; Gordon R Stewart; Sachi Okamoto; Jie Liu; Lubbert Dijkhuizen; Lindsay D Eltis
Journal: J Biol Chem Date: 2008-10-27 Impact factor: 5.157

6. Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis.

Authors: Olga Danilchanka; Claudia Mailaender; Michael Niederweis
Journal: Antimicrob Agents Chemother Date: 2008-05-05 Impact factor: 5.191

7. High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling.

Authors: Priscille Brodin; Yannick Poquet; Florence Levillain; Isabelle Peguillet; Gerald Larrouy-Maumus; Martine Gilleron; Fanny Ewann; Thierry Christophe; Denis Fenistein; Jichan Jang; Mi-Seon Jang; Sei-Jin Park; Jean Rauzier; Jean-Philippe Carralot; Rachel Shrimpton; Auguste Genovesio; Jesus A Gonzalo-Asensio; Germain Puzo; Carlos Martin; Roland Brosch; Graham R Stewart; Brigitte Gicquel; Olivier Neyrolles
Journal: PLoS Pathog Date: 2010-09-09 Impact factor: 6.823