| Literature DB >> 17018852 |
Ilya Shamovsky1, Evgeny Nudler.
Abstract
Large noncoding RNAs (lncRNAs) have emerged as key players in regulating various fundamental cellular processes. Recent reports identify a functional lncRNA, Evf-2, that operates during development to control the expression of specific homeodomain proteins, and they provide important insights into the mechanism of cooperation between a newly discovered nuclear receptor co-repressor protein (SLIRP) and steroid receptor activator RNA. Evf-2 is the first example of lncRNA directly involved in organogenesis in vertebrates.Entities:
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Year: 2006 PMID： 17018852 DOI： 10.1126/stke.3552006pe40
Source DB: PubMed Journal: Sci STKE ISSN： 1525-8882