Literature DB >> 17011786

Tissue-engineered trachea: History, problems and the future.

Qiang Tan1, Rudolf Steiner, Simon P Hoerstrup, Walter Weder.   

Abstract

This review tries to summarize the efforts over the past 20 years to construct a tissue-engineered trachea. After illustrating the main technical bottlenecks faced nowadays, we discuss what might be the solutions to these bottlenecks. You may find out why the focus in this research field shifts dramatically from the construction of a tubular cartilage tissue to reepithelialization and revascularization of the prosthesis. In the end we propose a novel concept of 'in vivo bioreactor', defined as the design of a perfusion system inside the scaffold, and explain its potential application in the construction of a tissue-engineered trachea.

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Year:  2006        PMID： 17011786     DOI： 10.1016/j.ejcts.2006.08.023

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN： 1010-7940            Impact factor:   4.191


  9 in total

1.  Engineered cartilaginous tubes for tracheal tissue replacement via self-assembly and fusion of human mesenchymal stem cell constructs.

Authors:  Anna D Dikina; Hannah A Strobel; Bradley P Lai; Marsha W Rolle; Eben Alsberg
Journal:  Biomaterials       Date:  2015-03-18       Impact factor: 12.479

2.  Clinic application of tissue engineered bronchus for lung cancer treatment.

Authors:  Qiang Tan; Ruijun Liu; Xiaoke Chen; Jingxiang Wu; Yinggen Pan; Shun Lu; Walter Weder; Qingquan Luo
Journal:  J Thorac Dis       Date:  2017-01       Impact factor: 2.895

3.  Bioengineered carina reconstruction using In-Vivo Bioreactor technique in human: proof of concept study.

Authors:  Yuanyuan Xu; Zhiyi Guo; Ruijun Liu; Hongwu Wang; Sheng Wang; Walter Weder; Yingen Pan; Jingxiang Wu; Heng Zhao; Qingquan Luo; Qiang Tan
Journal:  Transl Lung Cancer Res       Date:  2020-06

4.  Tracheal reconstruction with a composite graft: fascial flap-wrapped allogenic aorta with external cartilage-ring support.

Authors:  Alain Wurtz; Ilir Hysi; Eric Kipnis; Christophe Zawadzki; Thomas Hubert; Ramadan Jashari; Marie-Christine Copin; Brigitte Jude
Journal:  Interact Cardiovasc Thorac Surg       Date:  2012-10-09

5.  Polymeric implant materials for the reconstruction of tracheal and pharyngeal mucosal defects in head and neck surgery.

Authors:  Dorothee Rickert
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2011-03-10

6.  Grand challenges in pediatric otolaryngology.

Authors:  James M Coticchia; David Cohen; Livjot Sachdeva
Journal:  Front Pediatr       Date:  2013-05-20       Impact factor: 3.418

Review 7.  Advances in tracheal reconstruction.

Authors:  Siba Haykal; Michael Salna; Thomas K Waddell; Stefan O Hofer
Journal:  Plast Reconstr Surg Glob Open       Date:  2014-08-07

8.  Effectiveness of Palatal Mucosa Graft in Surgical Treatment of Sub-Glottic Stenosis.

Authors:  Umit Aydogmus; Adem Topkara; Metin Akbulut; Adem Ozkan; Figen Turk; Barbaros Sahin; Gokhan Yuncu
Journal:  Clin Exp Otorhinolaryngol       Date:  2016-07-02       Impact factor: 3.372

9.  A Modular Strategy to Engineer Complex Tissues and Organs.

Authors:  Anna D Dikina; Daniel S Alt; Samuel Herberg; Alexandra McMillan; Hannah A Strobel; Zijie Zheng; Meng Cao; Bradley P Lai; Oju Jeon; Victoria Ivy Petsinger; Calvin U Cotton; Marsha W Rolle; Eben Alsberg
Journal:  Adv Sci (Weinh)       Date:  2018-02-14       Impact factor: 16.806
  9 in total

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