OBJECTIVE: To evaluate prospectively the association between intakes of fish, marine fatty acids, and bladder cancer risk in two ongoing cohorts, the Health Professionals Follow-up Study and the Nurses' Health Study. METHODS: During 16 and 18 years of follow-up, 501 and 235 incident cases of bladder cancer were diagnosed among men and women, respectively. Cox proportional hazard models were used to estimate incidence rate ratios (RR) and 95% confidence intervals (CI) between fish intake and bladder cancer risk adjusting for age, total caloric intake, pack-years of cigarette smoking, and current smoking. RESULTS: We observed no significant overall association between total fish intake and bladder cancer risk, even when we compared >/=1 servings of fish per day to fish intake </=1-3 servings per month. Among men, a statistically significant lower risk of bladder cancer was observed among men consuming fish or high marine fatty acid, after excluding the first 4 years of follow-up (MV RR = 0.60; 95% CI, 0.38-0.94, for >/=1 total fish servings per day compared to </=1-3 servings per month). CONCLUSIONS: Overall, these findings suggest that fish intake is not likely to be appreciably associated with the risk of bladder cancer.
OBJECTIVE: To evaluate prospectively the association between intakes of fish, marine fatty acids, and bladder cancer risk in two ongoing cohorts, the Health Professionals Follow-up Study and the Nurses' Health Study. METHODS: During 16 and 18 years of follow-up, 501 and 235 incident cases of bladder cancer were diagnosed among men and women, respectively. Cox proportional hazard models were used to estimate incidence rate ratios (RR) and 95% confidence intervals (CI) between fish intake and bladder cancer risk adjusting for age, total caloric intake, pack-years of cigarette smoking, and current smoking. RESULTS: We observed no significant overall association between total fish intake and bladder cancer risk, even when we compared >/=1 servings of fish per day to fish intake </=1-3 servings per month. Among men, a statistically significant lower risk of bladder cancer was observed among men consuming fish or high marine fatty acid, after excluding the first 4 years of follow-up (MV RR = 0.60; 95% CI, 0.38-0.94, for >/=1 total fish servings per day compared to </=1-3 servings per month). CONCLUSIONS: Overall, these findings suggest that fish intake is not likely to be appreciably associated with the risk of bladder cancer.
Authors: Maree T Brinkman; Margaret R Karagas; Michael S Zens; Alan R Schned; Raoul C Reulen; Maurice P Zeegers Journal: Br J Nutr Date: 2011-05-10 Impact factor: 3.718
Authors: Reno C Leeming; Stella Koutros; Margaret R Karagas; Dalsu Baris; Molly Schwenn; Alison Johnson; Michael S Zens; Alan R Schned; Nathaniel Rothman; Debra T Silverman; Michael N Passarelli Journal: Eur J Nutr Date: 2022-06-27 Impact factor: 5.614
Authors: Mostafa Dianatinasab; Anke Wesselius; Tessa de Loeij; Amin Salehi-Abargouei; Evan Y W Yu; Mohammad Fararouei; Maree Brinkman; Piet van den Brandt; Emily White; Elisabete Weiderpass; Florence Le Calvez-Kelm; Marc J Gunter; Inge Huybrechts; Fredrik Liedberg; Guri Skeie; Anne Tjonneland; Elio Riboli; Maurice P Zeegers Journal: Eur J Epidemiol Date: 2021-05-25 Impact factor: 8.082