| Literature DB >> 16997123 |
Brenda Paula Figueiredo de Almeida Gomes1, Morgana Eli Vianna, Neylla Teixeira Sena, Alexandre Augusto Zaia, Caio Cezar Randi Ferraz, Francisco José de Souza Filho.
Abstract
The aim of this study was to investigate the antimicrobial activity of calcium hydroxide (Ca(OH)2) combined with 2% chlorhexidine gluconate (CHX) gel against endodontic pathogens and to compare the results with the ones achieved by Ca(OH)2 mixed with sterile water and by CHX gel alone. Two methods were used: the agar diffusion test and the direct contact test. Ca(OH)2 + 2% CHX gel produced inhibitory zones ranging from 2.84 to 6.5 mm, and required from 30 seconds to 6 hours to eliminate all tested microorganisms. However, 2% CHX gel showed the largest microbial growth zones from 4.33 to 21.67 mm, and required 1 minute or less to inhibit all tested microorganisms. A paste of Ca(OH)2 plus sterile water inhibited only the microorganisms with which it was in direct contact and required from 30 seconds to 24 hours to kill all tested microorganisms. In conclusion, 2% CHX gel + Ca(OH)2 showed better antimicrobial activity than Ca(OH)2 manipulated with sterile water.Entities:
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Year: 2006 PMID： 16997123 DOI： 10.1016/j.tripleo.2006.04.010
Source DB: PubMed Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod ISSN： 1079-2104