Jerin Jose1, Shoba Krishnamma2, Faizal Peedikayil3, Shibu Aman4, Nithya Tomy5, Jithin Pulickal Mariodan6. 1. Junior Resident, Department of Conservative Dentistry and Endodontics, Government Dental College , Kottayam, Kerala, India . 2. Professor and Head of Department, Department of Conservative Dentistry and Endodontics, Government Dental College , Kottayam, Kerala, India . 3. Professor, Department of Pedodontics and Preventive Dentistry, Kannur Dental College , Kannur, India . 4. Assistant Professor, Department of Conservative Dentistry and Endodontics, Government Dental College , Kottayam, Kerala, India . 5. Junior Resident, Department of Pedodontics and Preventive Dentistry, Kannur Dental College , Kannur, India . 6. Junior Resident, Department of Pedodontics and Preventive Dentistry, Koorg Institute of Dental Sciences , Virajpettu, India .
Abstract
INTRODUCTION: Debridement and disinfection of the root canal system is a critical step in endodontic treatment. Most of the irrigants presently used in the endodontic treatment can have an impact on the microbes surviving in the biofilm but none of them are able to do all of the required tasks. Researches are going on its full swing in order to produce an endodontic irrigant having ideal properties. AIM: To compare the antimicrobial efficacy of different irrigants like QMiX, guava leaf extract, aloevera extract, 2.5% sodium hypochlorite and 2% chlorhexidine gluconate against Enterococcus faecalis and Candida albicans. MATERIALS AND METHODS: The antimicrobial activity was determined using agar diffusion test. The solutions were divided into five groups: Group I- QMiX, Group II- Guava leaf extract and Group III-Aloevera extract, Group IV-2.5% Sodium hypochlorite and Group V-2% Chlorhexidine. The zones of inhibition of growth were recorded. RESULTS: Statistical analysis was performed using one way ANOVA with post-hoc Tukey's HSD. Values obtained were statistically analyzed (p<0.05). QMiX showed maximum inhibitory effect against Enterococcus faecalis and Candida albicans followed by, 2% chlorhexidine, 2.5% sodium hypochlorite, guava leaf extract and aloevera extract. Results obtained were statistically significant. CONCLUSION: Guava leaf extract showed significant inhibitory effects against Enterococcus faecalis and Candida albicans. QMiX demonstrated the best results among the tested solutions and can be considered as a potential alternative to existing root canal irrigants.
INTRODUCTION: Debridement and disinfection of the root canal system is a critical step in endodontic treatment. Most of the irrigants presently used in the endodontic treatment can have an impact on the microbes surviving in the biofilm but none of them are able to do all of the required tasks. Researches are going on its full swing in order to produce an endodontic irrigant having ideal properties. AIM: To compare the antimicrobial efficacy of different irrigants like QMiX, guava leaf extract, aloevera extract, 2.5% sodium hypochlorite and 2% chlorhexidine gluconate against Enterococcus faecalis and Candida albicans. MATERIALS AND METHODS: The antimicrobial activity was determined using agar diffusion test. The solutions were divided into five groups: Group I- QMiX, Group II- Guava leaf extract and Group III-Aloevera extract, Group IV-2.5% Sodium hypochlorite and Group V-2% Chlorhexidine. The zones of inhibition of growth were recorded. RESULTS: Statistical analysis was performed using one way ANOVA with post-hoc Tukey's HSD. Values obtained were statistically analyzed (p<0.05). QMiX showed maximum inhibitory effect against Enterococcus faecalis and Candida albicans followed by, 2% chlorhexidine, 2.5% sodium hypochlorite, guava leaf extract and aloevera extract. Results obtained were statistically significant. CONCLUSION:Guava leaf extract showed significant inhibitory effects against Enterococcus faecalis and Candida albicans. QMiX demonstrated the best results among the tested solutions and can be considered as a potential alternative to existing root canal irrigants.
Authors: Margaret Soo Yee Chia; Abhishek Parolia; Benjamin Syek Hur Lim; Jayakumar Jayaraman; Isabel Cristina Celerino de Moraes Porto Journal: Restor Dent Endod Date: 2020-05-21