Literature DB >> 16980010

Prognosis after liver transplantation predicted by preoperative MELD score.

D J Kim1, S-K Lee, J W Jo, S J Kim, C H D Kwon, J W Park, Y S Han, J B Park.   

Abstract

The model for end-stage liver disease (MELD) has been an excellent predictor of 3-month mortality among cirrhotic patients awaiting orthotopic liver transplantation (OLT). The aim of this study was to evaluate whether the preoperative MELD score predicts short-term prognosis after OLT. We enrolled 98 adult liver transplant patients performed at our center from January 2001 to December 2002. In univariate analysis of risk factors for death within 3 and 6 months after liver transplantation, serum total bilirubin, creatinine, MELD score, hyponatremia with ascites, Child-Turcotte-Pugh (CTP) score were statistically significant parameters (P < .05). By logistic regression, none of the risk factors were subjected to multivariate analysis showed statistical significance. The odds ratios of the MELD score, hyponatremia with ascites, CTP score within 3 months were 0.997, 1.151, and 0.726 with 95% confidence intervals of [0.899, 1.105], [0.102, 12.959], and [0.389, 1.352], respectively. The odds ratio of MELD score, hyponatremia with ascites, CTP score within 6 months were 0.996, 0.914, and 0.764, with 95% confidence intervals of [0.901, 1.102], [0.089, 9.369], and [0.417, 1.401], respectively. Although MELD score has been a good predictor of short-term prognosis before OLT, MELD did not show an influence on the short-term prognosis after liver transplantation in this study.

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Year:  2006        PMID: 16980010     DOI: 10.1016/j.transproceed.2006.06.031

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  6 in total

1.  Pre-transplant MELD and sodium MELD scores are poor predictors of graft failure and mortality after liver transplantation.

Authors:  Jacek B Cywinski; Edward J Mascha; Jing You; Daniel I Sessler; Leonardo Kapural; Maged Argalious; Brian M Parker
Journal:  Hepatol Int       Date:  2011-02-17       Impact factor: 6.047

2.  Hyponatremia as a predictor of outcome and mortality: results from a second-level urban emergency department population.

Authors:  Anna Giulia Falchi; Camilla Mascolo; Vincenzo Sepe; Carmelo Libetta; Elisa Bonadeo; Riccardo Albertini; Federica Manzoni; Stefano Perlini
Journal:  Ir J Med Sci       Date:  2022-02-20       Impact factor: 1.568

Review 3.  Clinical Implications, Evaluation, and Management of Hyponatremia in Cirrhosis.

Authors:  Dibya L Praharaj; Anil C Anand
Journal:  J Clin Exp Hepatol       Date:  2021-09-16

4.  Aorto-hepatic bypass in liver transplantation in the MELD-era: outcomes after supraceliac and infrarenal bypasses.

Authors:  Richard Hummel; Sabrina Irmscher; Christina Schleicher; Norbert Senninger; Jens G Brockmann; Heiner H Wolters
Journal:  Surg Today       Date:  2013-03-05       Impact factor: 2.549

5.  Implications of Hyponatremia in Liver Transplantation.

Authors:  Sertac Cimen; Sanem Guler; Subhashini Ayloo; Michele Molinari
Journal:  J Clin Med       Date:  2014-12-29       Impact factor: 4.241

6.  Predictors of Mortality During Initial Liver Transplant Hospitalization and Investigation of Causes of Death.

Authors:  Ni Gong; Chao Jia; He Huang; Jing Liu; XueTing Huang; Qiquan Wan
Journal:  Ann Transplant       Date:  2020-12-04       Impact factor: 1.530

  6 in total

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