Anna Giulia Falchi1, Camilla Mascolo2, Vincenzo Sepe3, Carmelo Libetta3, Elisa Bonadeo4, Riccardo Albertini5, Federica Manzoni6, Stefano Perlini7. 1. Emergency Department, IRCCS Policlinico San Matteo Foundation, Pavia, Italy. a.falchi@smatteo.pv.it. 2. Cardiology Postgraduate Training Program, University of Pavia, Pavia, Italy. 3. Nephrology Department, IRCCS Policlinico San Matteo Foundation, Pavia, Italy. 4. UOC Direzione Medica Di Presidio, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. 5. Laboratory of Clinical Chemistry, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. 6. Biometry and Clinical Epidemiology, San Matteo Hospital Foundation, Pavia, Italy. 7. Emergency Department, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
Abstract
BACKGROUND: Hyponatremia is the most common electrolyte disorder and it has been associated with increased mortality. AIMS: This study evaluated hyponatremia as a prognostic factor for severity and mortality. METHODS: We compared the prevalence of hyponatremia among patients who died during the year 2017 (from 1 January 2017 to 31 December 2017) with the prevalence of hyponatremia among subgroups of patients, i.e. outpatients, patients hospitalized for more than 2 days and patients admitted in the intensive care unit (ICU). We also described the mortality rate and the prevalence of comorbidities among hyponatremic patients, according to hyponatremia degree (slight, moderate, severe), basal characteristics, comorbidities and their outcome (discharged, hospitalized or died). RESULTS: In our population of a public hospital setting, hyponatremia was present at admission in 17% of deaths, and the comparison between hyponatremic and normonatremic patients in terms of mortality confirms the hypothesis that this disorder is in anyway strictly associated with vulnerability and with a poor prognosis. CONCLUSIONS: We conclude that hyponatremia is a predictive marker for a bad clinical course, therefore patients with this electrolyte disorder should be carefully monitored.
BACKGROUND: Hyponatremia is the most common electrolyte disorder and it has been associated with increased mortality. AIMS: This study evaluated hyponatremia as a prognostic factor for severity and mortality. METHODS: We compared the prevalence of hyponatremia among patients who died during the year 2017 (from 1 January 2017 to 31 December 2017) with the prevalence of hyponatremia among subgroups of patients, i.e. outpatients, patients hospitalized for more than 2 days and patients admitted in the intensive care unit (ICU). We also described the mortality rate and the prevalence of comorbidities among hyponatremic patients, according to hyponatremia degree (slight, moderate, severe), basal characteristics, comorbidities and their outcome (discharged, hospitalized or died). RESULTS: In our population of a public hospital setting, hyponatremia was present at admission in 17% of deaths, and the comparison between hyponatremic and normonatremic patients in terms of mortality confirms the hypothesis that this disorder is in anyway strictly associated with vulnerability and with a poor prognosis. CONCLUSIONS: We conclude that hyponatremia is a predictive marker for a bad clinical course, therefore patients with this electrolyte disorder should be carefully monitored.
Authors: Scott W Biggins; W Ray Kim; Norah A Terrault; Sammy Saab; Vijay Balan; Thomas Schiano; Joanne Benson; Terry Therneau; Walter Kremers; Russell Wiesner; Patrick Kamath; Goran Klintmalm Journal: Gastroenterology Date: 2006-05 Impact factor: 22.682
Authors: Mihai Gheorghiade; Joseph S Rossi; William Cotts; David D Shin; Anne S Hellkamp; Ileana L Piña; Gregg C Fonarow; Teresa DeMarco; Daniel F Pauly; Joseph Rogers; Thomas G DiSalvo; Javed Butler; Joshua M Hare; Gary S Francis; Wendy Gattis Stough; Christopher M O'Connor Journal: Arch Intern Med Date: 2007-10-08