Literature DB >> 16962774

Fluorinated and hemifluorinated surfactants derived from maltose: synthesis and application to handling membrane proteins in aqueous solution.

Ange Polidori1, Marc Presset, Florence Lebaupain, Bruno Ameduri, Jean-Luc Popot, Cécile Breyton, Bernard Pucci.   

Abstract

Two novel fluorinated surfactants have been obtained by grafting by radical reaction either a fluorocarbon or an ethyl end-capped fluorocarbon chain onto the double bond of beta-D-allyl maltose. The two compounds thus obtained form polydisperse aggregates in water. They can keep membrane proteins water-soluble, but the protein/surfactant complexes are polydisperse, which affects neither the native state nor the stability of the proteins.

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Year:  2006        PMID: 16962774     DOI: 10.1016/j.bmcl.2006.08.070

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  4 in total

1.  Micellar and biochemical properties of (hemi)fluorinated surfactants are controlled by the size of the polar head.

Authors:  Cécile Breyton; Frank Gabel; Maher Abla; Yves Pierre; Florence Lebaupain; Grégory Durand; Jean-Luc Popot; Christine Ebel; Bernard Pucci
Journal:  Biophys J       Date:  2009-08-19       Impact factor: 4.033

Review 2.  Membrane proteins, detergents and crystals: what is the state of the art?

Authors:  Patrick J Loll
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2014-11-28       Impact factor: 1.056

3.  A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins.

Authors:  Pil Seok Chae; Søren G F Rasmussen; Rohini R Rana; Kamil Gotfryd; Andrew C Kruse; Aashish Manglik; Kyung Ho Cho; Shailika Nurva; Ulrik Gether; Lan Guan; Claus J Loland; Bernadette Byrne; Brian K Kobilka; Samuel H Gellman
Journal:  Chemistry       Date:  2012-06-22       Impact factor: 5.236

4.  Use of dynamic light scattering and small-angle X-ray scattering to characterize new surfactants in solution conditions for membrane-protein crystallization.

Authors:  Mohamed Dahani; Laurie Anne Barret; Simon Raynal; Colette Jungas; Pétra Pernot; Ange Polidori; Françoise Bonneté
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2015-06-27       Impact factor: 1.056

  4 in total

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