Literature DB >> 16960741

Sclerosing polidocanol injections in chronic painful tennis elbow-promising results in a pilot study.

Eva Zeisig1, Lars Ohberg, Håkan Alfredson.   

Abstract

Sclerosing polidocanol injections targeting the area with neovessels (vascularity) have been demonstrated to give promising clinical results in patients with chronic painful Achilles and patellar tendinosis. Recently, we demonstrated vascularity in the extensor origin in patients with chronic painful tennis elbow, but not in controls with pain-free elbows. In this pilot study, 11 patients (four men and seven women, mean age 46 years) with the diagnosis of tennis elbow in altogether 13 elbows, were included. All patients had a long duration of pain symptoms (mean 23 months), and ultrasonography (US) + colour Doppler (CD) examination showed structural tendon changes with hypo-echoic areas, and a vascularity, corresponding to the painful area in the extensor origin. All patients were treated with US- and CD-guided injections of the sclerosing substance polidocanol, targeting the area with vascularity. At 8-month follow-up after treatment, there was a good clinical result in 11/13 elbows. Extensor origin pain during wrist loading activities (recorded on a VAS-scale) was significantly reduced (mean VAS from 75 to 34; P < 0.003), and maximal grip strength was significantly increased (from 29 to 40 kg; P < 0.025). Our findings indicate that one treatment with sclerosing polidocanol injections, targeting the area with vascularity in the extensor origin, has a potential to reduce the tendon pain and increase grip strength, in patients with chronic painful tennis elbow.

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Year:  2006        PMID: 16960741     DOI: 10.1007/s00167-006-0156-0

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  25 in total

1.  Where is the pain coming from in tendinopathy? It may be biochemical, not only structural, in origin.

Authors:  K M Khan; J L Cook; N Maffulli; P Kannus
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2.  Diagnostic value of ultrasonography in epicondylitis.

Authors:  Tobias Torp-Pedersen; Sorren Torp-Pedersen; Henning Bliddal
Journal:  Ann Intern Med       Date:  2002-05-21       Impact factor: 25.391

3.  Botulinum toxin injection in the treatment of tennis elbow. A double-blind, randomized, controlled, pilot study.

Authors:  M J Hayton; A J A Santini; P J Hughes; S P Frostick; I A Trail; J K Stanley
Journal:  J Bone Joint Surg Am       Date:  2005-03       Impact factor: 5.284

4.  Tennis elbow: its course, natural history, conservative and surgical management.

Authors:  R W Coonrad; W R Hooper
Journal:  J Bone Joint Surg Am       Date:  1973-09       Impact factor: 5.284

5.  Vascular NK-1 receptor occurrence in normal and chronic painful Achilles and patellar tendons: studies on chemically unfixed as well as fixed specimens.

Authors:  Sture Forsgren; Patrik Danielson; Håkan Alfredson
Journal:  Regul Pept       Date:  2005-03-30

6.  Corticosteroid injections for lateral epicondylitis: a systematic overview.

Authors:  W J Assendelft; E M Hay; R Adshead; L M Bouter
Journal:  Br J Gen Pract       Date:  1996-04       Impact factor: 5.386

7.  Neovascularisation in chronic painful patellar tendinosis--promising results after sclerosing neovessels outside the tendon challenge the need for surgery.

Authors:  Håkan Alfredson; Lars Ohberg
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2004-11-26       Impact factor: 4.342

8.  Ultrasound guided sclerosis of neovessels in painful chronic Achilles tendinosis: pilot study of a new treatment.

Authors:  Lars Ohberg; H Alfredson
Journal:  Br J Sports Med       Date:  2002-06       Impact factor: 13.800

9.  Sclerosing therapy in chronic Achilles tendon insertional pain-results of a pilot study.

Authors:  Lars Ohberg; Håkan Alfredson
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2003-08-19       Impact factor: 4.342

10.  Is vasculo-neural ingrowth the cause of pain in chronic Achilles tendinosis? An investigation using ultrasonography and colour Doppler, immunohistochemistry, and diagnostic injections.

Authors:  Håkan Alfredson; Lars Ohberg; Sture Forsgren
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2003-08-09       Impact factor: 4.342

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  19 in total

1.  Topical polidocanol application in combination with static stretching in tendinopathies: a prospective pilot study.

Authors:  Matthias Gatz; Simone Schrading; Timm Dirrichs; Marcel Betsch; Markus Tingart; Björn Rath; Christiane Kuhl; Valentin Quack
Journal:  Muscles Ligaments Tendons J       Date:  2017-05-10

Review 2.  Lateral epicondylitis in tennis: update on aetiology, biomechanics and treatment.

Authors:  Thomas De Smedt; Andy de Jong; Wim Van Leemput; Dossche Lieven; Francis Van Glabbeek
Journal:  Br J Sports Med       Date:  2007-07-06       Impact factor: 13.800

3.  Structure-function relationships in tendons: a review.

Authors:  M Benjamin; E Kaiser; S Milz
Journal:  J Anat       Date:  2008-03       Impact factor: 2.610

Review 4.  Image-guided elbow interventions: a literature review of interventional treatment options.

Authors:  Alan Sorani; Robert Campbell
Journal:  Br J Radiol       Date:  2015-08-19       Impact factor: 3.039

5.  Neovascularisation in flexor carpi ulnaris tendinopathy: novel combined sclerosing therapy and eccentric training of the forearms in athletics' wrist pain.

Authors:  Karsten Knobloch; Andreas Gohritz; Marcus Spies; Peter M Vogt
Journal:  BMJ Case Rep       Date:  2009-02-02

6.  [Conservative treatment of chronic tendinopathies].

Authors:  P Diehl; H Gollwitzer; J Schauwecker; T Tischer; L Gerdesmeyer
Journal:  Orthopade       Date:  2014-02       Impact factor: 1.087

Review 7.  Interventional musculoskeletal US: an update on materials and methods.

Authors:  Guido Robotti; Maria Grazia Canepa; Chandra Bortolotto; Ferdinando Draghi
Journal:  J Ultrasound       Date:  2013-04-30

8.  Sclerosing therapy and eccentric training in flexor carpi radialis tendinopathy in a tennis player.

Authors:  Karsten Knobloch; Marcus Spies; Kay H Busch; Peter M Vogt
Journal:  Br J Sports Med       Date:  2007-05-11       Impact factor: 13.800

9.  Eccentric treatment for patellar tendinopathy: a prospective randomised short-term pilot study of two rehabilitation protocols.

Authors:  Anna Frohm; Tönu Saartok; Kjartan Halvorsen; Per Renström
Journal:  Br J Sports Med       Date:  2007-02-08       Impact factor: 13.800

Review 10.  Treatment of tendinopathy: what works, what does not, and what is on the horizon.

Authors:  Brett M Andres; George A C Murrell
Journal:  Clin Orthop Relat Res       Date:  2008-04-30       Impact factor: 4.176

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