Literature DB >> 16956199

Preparation of a psammaplysene-based library.

Savvas N Georgiades1, Jon Clardy.   

Abstract

A 28-member focused library, based on the pseudosymmetric template of the marine alkaloids psammaplysenes, was prepared from combinations of components that were, in turn, derived from 4-iodophenol.

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Year:  2006        PMID: 16956199      PMCID: PMC2522302          DOI: 10.1021/ol061599w

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  7 in total

1.  Highly satisfactory procedures for the Pd-catalyzed cross coupling of aryl electrophiles with in situ generated alkynylzinc derivatives.

Authors:  L Anastasia
Journal:  Org Lett       Date:  2001-10-04       Impact factor: 6.005

2.  A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells.

Authors:  Tweeny R Kau; Frank Schroeder; Shivapriya Ramaswamy; Cheryl L Wojciechowski; Jean J Zhao; Thomas M Roberts; Jon Clardy; William R Sellers; Pamela A Silver
Journal:  Cancer Cell       Date:  2003-12       Impact factor: 31.743

Review 3.  From protein domains to drug candidates-natural products as guiding principles in the design and synthesis of compound libraries.

Authors:  Rolf Breinbauer; Ingrid R Vetter; Herbert Waldmann
Journal:  Angew Chem Int Ed Engl       Date:  2002-08-16       Impact factor: 15.336

4.  The psammaplysenes, specific inhibitors of FOXO1a nuclear export.

Authors:  Frank C Schroeder; Tweeny R Kau; Pamela A Silver; Jon Clardy
Journal:  J Nat Prod       Date:  2005-04       Impact factor: 4.050

5.  Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export.

Authors:  Savvas N Georgiades; Jon Clardy
Journal:  Org Lett       Date:  2005-09-15       Impact factor: 6.005

6.  A reiterative approach to 2,3-disubstituted naphthalenes and anthracenes

Authors: 
Journal:  Org Lett       Date:  2000-01       Impact factor: 6.005

7.  Fast, efficient and selective deprotection of the tert-butoxycarbonyl (Boc) group using HCl/dioxane (4 m).

Authors:  G Han; M Tamaki; V J Hruby
Journal:  J Pept Res       Date:  2001-10
  7 in total
  3 in total

1.  Induction of apoptosis in endometrial cancer cells by psammaplysene A involves FOXO1.

Authors:  Emily Berry; Jennifer L Hardt; Jon Clardy; John R Lurain; J Julie Kim
Journal:  Gynecol Oncol       Date:  2008-11-28       Impact factor: 5.482

2.  A short and efficient total synthesis of the bromotyrosine-derived alkaloid psammaplysene A.

Authors:  Jingjing Xu; Kai Wang; Jinlong Wu
Journal:  RSC Adv       Date:  2018-04-12       Impact factor: 4.036

3.  Isolation, synthesis, and biological activity of aphrocallistin, an adenine-substituted bromotyramine metabolite from the Hexactinellida sponge Aphrocallistes beatrix.

Authors:  Amy E Wright; Gregory P Roth; Jennifer K Hoffman; Daniela B Divlianska; Diana Pechter; Susan H Sennett; Esther A Guzmán; Patricia Linley; Peter J McCarthy; Tara P Pitts; Shirley A Pomponi; John K Reed
Journal:  J Nat Prod       Date:  2009-06       Impact factor: 4.050

  3 in total

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