| Literature DB >> 16954312 |
Vincent H Tam1, Samer Kabbara, Rosa F Yeh, Robert H Leary.
Abstract
Monte Carlo simulations are increasingly used to predict pharmacokinetic variability of antimicrobials in a population. We investigated the sample size necessary to provide robust pharmacokinetic predictions. To obtain reasonably robust predictions, a nonparametric model derived from a sample population size of >/=50 appears to be necessary as the input information.Mesh:
Substances:
Year: 2006 PMID: 16954312 PMCID: PMC1635223 DOI: 10.1128/AAC.00337-06
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191