| Literature DB >> 16949126 |
M Leslie Hanna1, Theodore M Tarasow, Julie Perkins.
Abstract
A systematically generated series of hydrazones were analyzed as potential inhibitors of anthrax lethal factor. The hydrazones were screened using one UV-based and two fluorescence-based in vitro assays. The study identified several inhibitors with IC50 values in the micromolar range, and importantly, significant differences in the types of inhibition were observed with the different assays.Entities:
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Year: 2006 PMID： 16949126 DOI： 10.1016/j.bioorg.2006.07.004
Source DB: PubMed Journal: Bioorg Chem ISSN： 0045-2068 Impact factor: 5.275