Literature DB >> 1692568

Kinetochore formation in experimentally undercondensed chromosomes.

T Haaf1, M Schmid.   

Abstract

Treatment of human and mouse cell cultures with the cytidine analogue 5-azadeoxycytidine and the AT-specific DNA ligand Hoechst 33258 dramatically inhibited condensation of the pericentromeric heterochromatin in several chromosomes. When stained with antikinetochore autoimmune sera, these experimentally undercondensed chromosomes showed kinetochores with preserved antigenicity. The undercondensed and normally condensed chromosomes share the major antigenic determinants of the kinetochore.

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Year:  1990        PMID： 1692568     DOI： 10.1007/bf00210805

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  12 in total

1.  Centromeric association and non-random distribution of centromeres in human tumour cells.

Authors:  T Haaf; M Schmid
Journal:  Hum Genet       Date:  1989-01       Impact factor: 4.132

2.  Preferential somatic pairing between homologous heterochromatic regions of human chromosomes.

Authors:  T Haaf; K Steinlein; M Schmid
Journal:  Am J Hum Genet       Date:  1986-03       Impact factor: 11.025

3.  Analysis of anticentromere autoantibodies using cloned autoantigen CENP-B.

Authors:  W C Earnshaw; P S Machlin; B J Bordwell; N F Rothfield; D W Cleveland
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205

4.  Decondensation of constitutive heterochromatin in L cell chromosomes by a benzimidazole compound ("33258 Hoechst").

Authors:  I Hilwig; A Gropp
Journal:  Exp Cell Res       Date:  1973-10       Impact factor: 3.905

5.  Indirect immunofluorescence of inactive centromeres as indicator of centromeric function.

Authors:  D Peretti; P Maraschio; S Lambiase; F Lo Curto; O Zuffardi
Journal:  Hum Genet       Date:  1986-05       Impact factor: 4.132

6.  Characterization of kinetochores in multicentric chromosomes.

Authors:  R P Zinkowski; B K Vig; D Broccoli
Journal:  Chromosoma       Date:  1986       Impact factor: 4.316

Review 7.  The formation, structure, and composition of the mammalian kinetochore and kinetochore fiber.

Authors:  C L Rieder
Journal:  Int Rev Cytol       Date:  1982

Review 8.  Heterochromatin, satellite DNA, and cell function. Structural DNA of eucaryotes may support and protect genes and aid in speciation.

Authors:  J J Yunis; W G Yasmineh
Journal:  Science       Date:  1971-12-17       Impact factor: 47.728

9.  5-Azacytidine-induced undercondensations in human chromosomes.

Authors:  M Schmid; T Haaf; D Grunert
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

10.  The kinetochore is part of the metaphase chromosome scaffold.

Authors:  W C Earnshaw; N Halligan; C Cooke; N Rothfield
Journal:  J Cell Biol       Date:  1984-01       Impact factor: 10.539
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  2 in total

1.  The organisation of repetitive DNA sequences on human chromosomes with respect to the kinetochore analysed using a combination of oligonucleotide primers and CREST anticentromere serum.

Authors:  A Mitchell; P Jeppesen; D Hanratty; J Gosden
Journal:  Chromosoma       Date:  1992-03       Impact factor: 4.316

2.  5-azacytidine produces differential undercondensation of alpha, beta and classical human satellite DNAs.

Authors:  J L Fernández; V Goyanes; S Pereira; C López-Fernández; J Gosálvez
Journal:  Chromosome Res       Date:  1994-01       Impact factor: 5.239
  2 in total

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