Literature DB >> 2420175

Preferential somatic pairing between homologous heterochromatic regions of human chromosomes.

T Haaf, K Steinlein, M Schmid.   

Abstract

The cytidine analog 5-azacytidine (5-azaC) induces an undercondensation of the heterochromatin in human chromosomes 1, 9, 15, 16, and Y when it is added in low concentrations to the late S-phase of growing lymphocyte cultures. In interphase nuclei, these heterochromatic regions are frequently somatically paired. The somatic pairing configurations are preserved up to metaphase stage in the 5-azaC-treated cultures and are thus susceptible to a direct microscopical examination. The statistical analysis of 1,000 somatic pairing configurations from 5-azaC-treated cells showed that the somatic pairing between the heterochromatic regions of homologous chromosomes is preferred over that between nonhomologous chromosomes.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 2420175      PMCID： PMC1684778     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  22 in total

1.  Attraction between centric heterochromatin of human chromosomes.

Authors:  M Schmid; W Vogel; W Krone
Journal:  Cytogenet Cell Genet       Date:  1975

2.  Distribution of human chromosomes on the metaphase plate using banding techniques.

Authors:  B Sele; P Jalbert; B van Cutsem; M Lucas; C Mouriquand; R Bouchez
Journal:  Hum Genet       Date:  1977-11-02       Impact factor: 4.132

3.  Spatial relations of human chromosomes identified by quinacrine fluorescence at metaphase. I. Mean interchromosomal distances and distances from the cell center.

Authors:  D Warburton; A F Naylor; F E Warburton
Journal:  Humangenetik       Date:  1973

4.  A fluorescence study of heterochromatin and nucleolar organization in the laboratory and tobacco mouse.

Authors:  A T Natarajan; A Gropp
Journal:  Exp Cell Res       Date:  1972-09       Impact factor: 3.905

5.  The internal order of the interphase nucleus.

Authors:  F Vogel; T M Schroeder
Journal:  Humangenetik       Date:  1974

6.  Nonrandom arrangement of human chromatin: topography of disomic markers X, Y, and 1h plus 1.

Authors:  H Hoehn; G M Martin
Journal:  Cytogenet Cell Genet       Date:  1973

7.  The location of four human satellite DNAs on human chromosomes.

Authors:  J R Gosden; A R Mitchell; R A Buckland; R P Clayton; H J Evans
Journal:  Exp Cell Res       Date:  1975-04       Impact factor: 3.905

8.  Modification of DAPI banding on human chromosomes by prestaining with a DNA-binding oligopeptide antibiotic, distamycin A.

Authors:  D Schweizer; P Ambros; M Andrle
Journal:  Exp Cell Res       Date:  1978-02       Impact factor: 3.905

9.  Relative position of trypsin banded homologous chromosomes in human (female) metaphase figures.

Authors:  L Hens; M Kirsch-Volders; C Susanne; H Galperin-Lemaître
Journal:  Humangenetik       Date:  1975-08-25

10.  [Non-random position of homologous chromosomes (no. 9 and YY) in interphase nuclei of human fibroblasts (author's transl)].

Authors:  M Spaeter
Journal:  Humangenetik       Date:  1975
View more
  10 in total

1.  Kinetochore formation in experimentally undercondensed chromosomes.

Authors:  T Haaf; M Schmid
Journal:  Hum Genet       Date:  1990-05       Impact factor: 4.132

Review 2.  Potential genetic functions of tandem repeated DNA sequence blocks in the human genome are based on a highly conserved "chromatin folding code".

Authors:  P Vogt
Journal:  Hum Genet       Date:  1990-03       Impact factor: 4.132

3.  Analysis of human extrachromosomal DNA elements originating from different beta-satellite subfamilies.

Authors:  G Assum; T Fink; T Steinbeisser; K J Fisel
Journal:  Hum Genet       Date:  1993-06       Impact factor: 4.132

4.  Spatial separation of parental genomes during mouse interspecific (Mus musculus x M. spretus) spermiogenesis.

Authors:  W Mayer; R Fundele; T Haaf
Journal:  Chromosome Res       Date:  2000       Impact factor: 5.239

5.  Somatic pairing between subtelomeric chromosome regions: implications for human genetic disease?

Authors:  K Stout; S van der Maarel; R R Frants; G W Padberg; H H Ropers; T Haaf
Journal:  Chromosome Res       Date:  1999       Impact factor: 5.239

6.  In human pachytene spermatocytes, SUMO protein is restricted to the constitutive heterochromatin.

Authors:  Catherine Metzler-Guillemain; Danielle Depetris; Judith J Luciani; Cecile Mignon-Ravix; Michael J Mitchell; Marie-Genevieve Mattei
Journal:  Chromosome Res       Date:  2008-07-04       Impact factor: 5.239

7.  Spatial separation of parental genomes in preimplantation mouse embryos.

Authors:  W Mayer; A Smith; R Fundele; T Haaf
Journal:  J Cell Biol       Date:  2000-02-21       Impact factor: 10.539

8.  Preferential occurrence of breast carcinomas with loss of chromosome 16q and der (16) t (1;16) / der (1;16) in middle-aged patients with hyperplasia of mammary glands.

Authors:  H Tsuda; T Takarabe; T Fukutomi; S Hirohashi
Journal:  Jpn J Cancer Res       Date:  2000-07

9.  Cytogenetic effect of 5-azacytidine in patients with hematological malignancies.

Authors:  Jessica Romy Tsuda; Rosimeire Segato; Waldênia Barbosa; Marília de Arruda Cardoso Smith; Spencer Luiz Marques Payão
Journal:  Rev Bras Hematol Hemoter       Date:  2011

10.  Distribution of segmental duplications in the context of higher order chromatin organisation of human chromosome 7.

Authors:  Grit Ebert; Anne Steininger; Robert Weißmann; Vivien Boldt; Allan Lind-Thomsen; Jana Grune; Stefan Badelt; Melanie Heßler; Matthias Peiser; Manuel Hitzler; Lars R Jensen; Ines Müller; Hao Hu; Peter F Arndt; Andreas W Kuss; Katrin Tebel; Reinhard Ullmann
Journal:  BMC Genomics       Date:  2014-06-29       Impact factor: 3.969
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.