Literature DB >> 16916872

Pars plana vitrectomy with peripheral retinotomy after injection of preoperative intravitreal tissue plasminogen activator: a modified procedure to drain massive subretinal haemorrhage.

Y Oshima1, M Ohji, Y Tano.   

Abstract

AIMS: To report outcome of a modified procedure for draining massive subretinal haemorrhages (SRHs).
METHODS: The charts of eight consecutive eyes from eight patients with massive SRHs extending to the periphery and involving two or more quadrants with haemorrhagic and bullous retinal detachment were reviewed. Tissue plasminogen activator (tPA) was injected intravitreally 12-24 h preoperatively; vitrectomy was carried out with peripheral retinotomy, drainage of the SRH from the retinotomy using perfluorocarbon liquid and gas tamponade with prone positioning postoperatively.
RESULTS: The preoperative visual acuities ranged from light perception to 20/200. Most of the subretinal haematomas moved postoperatively to the vitreous cavity through the peripheral retinotomy using perfluorocarbon liquid. Residual SRHs were drained from the anterior chamber at the bedside after prone positioning overnight. SRH recurred in one eye 14 months postoperatively and was successfully retreated. No other serious complications developed. The final visual acuity improved in seven eyes (range 20/1000-20/60). Polypoidal lesions in choroidal vasculatures were present in three of seven patients.
CONCLUSIONS: The technique seems safe and effective for treating massive SRH. However, visual recovery is limited by the underlying macular pathology. Polypoidal choroidal vasculopathy, other than age-related macular degeneration, may be another cause of massive SRHs.

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Year:  2006        PMID: 16916872      PMCID: PMC1857597          DOI: 10.1136/bjo.2006.101444

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  30 in total

1.  Surgical treatment of submacular hemorrhage associated with idiopathic polypoidal choroidal vasculopathy.

Authors:  F Shiraga; T Matsuo; S Yokoe; I Takasu; T Okanouchi; H Ohtsuki; H E Grossniklaus
Journal:  Am J Ophthalmol       Date:  1999-08       Impact factor: 5.258

2.  A study of the ability of tissue plasminogen activator to diffuse into the subretinal space after intravitreal injection in rabbits.

Authors:  M Kamei; K Misono; H Lewis
Journal:  Am J Ophthalmol       Date:  1999-12       Impact factor: 5.258

3.  Planned two-step vitrectomy for extremely large and thick subretinal hematoma.

Authors:  T Matsuo; F Shiraga; I Takasu
Journal:  Acta Ophthalmol Scand       Date:  2001-10

4.  Pars plana vitrectomy, subretinal injection of tissue plasminogen activator, and fluid-gas exchange for displacement of thick submacular hemorrhage in age-related macular degeneration.

Authors:  C L Haupert; B W McCuen; G J Jaffe; E R Steuer; T A Cox; C A Toth; S Fekrat; E A Postel
Journal:  Am J Ophthalmol       Date:  2001-02       Impact factor: 5.258

5.  Treatment of submacular hemorrhage with low-dose intravitreal tissue plasminogen activator injection and pneumatic displacement.

Authors:  B A Handwerger; B A Blodi; S R Chandra; T W Olsen; T S Stevens
Journal:  Arch Ophthalmol       Date:  2001-01

6.  Quantitative effect of intravitreally injected tissue plasminogen activator and gas on subretinal hemorrhage.

Authors:  L Hesse; B Schroeder; G Heller; P Kroll
Journal:  Retina       Date:  2000       Impact factor: 4.256

7.  Management of submacular hemorrhage with intravitreous tissue plasminogen activator injection and pneumatic displacement.

Authors:  A S Hassan; M W Johnson; T E Schneiderman; C D Regillo; P E Tornambe; L S Poliner; B A Blodi; S G Elner
Journal:  Ophthalmology       Date:  1999-10       Impact factor: 12.079

8.  Polypoidal choroidal vasculopathy: incidence, demographic features, and clinical characteristics.

Authors:  Kenichiro Sho; Kanji Takahashi; Haruhiko Yamada; Mitsumasa Wada; Yoshimi Nagai; Tsuyoshi Otsuji; Maki Nishikawa; Yumiko Mitsuma; Yukari Yamazaki; Miyo Matsumura; Masanobu Uyama
Journal:  Arch Ophthalmol       Date:  2003-10

9.  Natural history of macular subretinal hemorrhage in age-related macular degeneration.

Authors:  A Scupola; G Coscas; G Soubrane; E Balestrazzi
Journal:  Ophthalmologica       Date:  1999       Impact factor: 3.250

10.  Pathogenesis of the vitreous cloud emanating from subretinal hemorrhage.

Authors:  Harvey Lincoff; Bogidar Madjarov; Norah Lincoff; Alexander Movshovich; Sandeep Saxena; D Jackson Coleman; Herman Schubert; Daniel Rosberger; Stephen McCormick; S McCormack
Journal:  Arch Ophthalmol       Date:  2003-01
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  8 in total

1.  [Subretinal surgery for massive hemorrhage].

Authors:  P Szurman
Journal:  Ophthalmologe       Date:  2012-07       Impact factor: 1.059

2.  The retinal tolerance to bevacizumab in co-application with a recombinant tissue plasminogen activator.

Authors:  Matthias Lüke; Kai Januschowski; Max Warga; Julia Beutel; Martin Leitritz; Faik Gelisken; Salvatore Grisanti; Toni Schneider; Christoph Lüke; Karl Ulrich Bartz-Schmidt; Peter Szurman
Journal:  Br J Ophthalmol       Date:  2007-03-23       Impact factor: 4.638

3.  Transconjunctival sutureless vitrectomy with tissue plasminogen activator, gas and intravitreal bevacizumab in the management of predominantly hemorrhagic age-related macular degeneration.

Authors:  Luis Arias; Jordi Monés
Journal:  Clin Ophthalmol       Date:  2010-02-18

4.  Treatment of massive subretinal hematoma associated with age-related macular degeneration using vitrectomy with intentional giant tear.

Authors:  Eisuke Isizaki; Seita Morishita; Takaki Sato; Masanori Fukumoto; Hiroyuki Suzuki; Teruyo Kida; Mari Ueki; Tsunehiko Ikeda
Journal:  Int Ophthalmol       Date:  2015-07-28       Impact factor: 2.031

Review 5.  Guidelines for the management of neovascular age-related macular degeneration by the European Society of Retina Specialists (EURETINA).

Authors:  Ursula Schmidt-Erfurth; Victor Chong; Anat Loewenstein; Michael Larsen; Eric Souied; Reinier Schlingemann; Bora Eldem; Jordi Monés; Gisbert Richard; Francesco Bandello
Journal:  Br J Ophthalmol       Date:  2014-09       Impact factor: 4.638

Review 6.  [Management of submacular hemorrhage : What, when, how?]

Authors:  Lars-Olof Hattenbach; Salvatore Grisanti; Nicolas Feltgen; Argyrios Chronopoulos
Journal:  Ophthalmologe       Date:  2020-09       Impact factor: 1.059

7.  23-Gauge vitrectomy with external drainage therapy as a novel procedure to displace massive submacular hemorrhage secondary to polypoidal choroidal vasculopathy.

Authors:  Hui Liu; Lu-Yi Zhang; Xiao-Xia Li; Miao-Qin Wu
Journal:  Medicine (Baltimore)       Date:  2016-08       Impact factor: 1.889

8.  Long-term clinical outcomes of submacular blood removal with isolated autologous retinal pigment epithelium-choroid patch graft transplantation in long-standing large-sized submacular hematomas: An Indian experience.

Authors:  Subhendu Kumar Boral; Deepak Agarwal; Arnab Das; Tushar Kanti Sinha
Journal:  Indian J Ophthalmol       Date:  2020-10       Impact factor: 1.848

  8 in total

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