Literature DB >> 32767098

[Management of submacular hemorrhage : What, when, how?]

Lars-Olof Hattenbach1, Salvatore Grisanti2, Nicolas Feltgen3, Argyrios Chronopoulos4.   

Abstract

BACKGROUND: Subretinal hemorrhage involving the macula is a typical complication in a variety of retinal diseases, whereby age-related macular degeneration (AMD) is by far the leading cause.
METHOD: A literature search was carried out in PubMed.
RESULTS: Numerous studies have demonstrated the effectiveness of various approaches to the management of submacular hemorrhage, including intravitreal anti-VEGF treatment, pneumatic displacement supported by fibrinolytic agents or surgical drainage. DISCUSSION: There is currently no consensus regarding evidence-based standard treatment for macular hemorrhage, although there is a trend towards minimally invasive approaches. Regardless of the choice of the primary treatment approach, the time to treatment and an accompanying intravitreal treatment with VEGF inhibitors are decisive for the functional outcome.

Entities:  

Keywords:  Age-related macular degeneration; Functional result; Intravitreal treatment; Minimally invasive procedures; Vascular endothelial growth factor inhibitors

Mesh:

Substances:

Year:  2020        PMID: 32767098     DOI: 10.1007/s00347-020-01192-5

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  56 in total

1.  Intravitreous injection of tissue plasminogen activator and gas in the treatment of submacular hemorrhage under various conditions.

Authors:  L O Hattenbach; C Klais; F H Koch; H O Gümbel
Journal:  Ophthalmology       Date:  2001-08       Impact factor: 12.079

2.  Management of acute submacular hemorrhage using recombinant tissue plasminogen activator and gas.

Authors:  L Hesse; J Schmidt; P Kroll
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1999-04       Impact factor: 3.117

3.  Natural history of subfoveal subretinal hemorrhage in age-related macular degeneration.

Authors:  R L Avery; S Fekrat; B S Hawkins; N M Bressler
Journal:  Retina       Date:  1996       Impact factor: 4.256

Review 4.  Pathophysiology and management of subretinal hemorrhage.

Authors:  M A Hochman; C M Seery; M A Zarbin
Journal:  Surv Ophthalmol       Date:  1997 Nov-Dec       Impact factor: 6.048

5.  Variations in the clinical course of submacular hemorrhage.

Authors:  M H Berrocal; M L Lewis; H W Flynn
Journal:  Am J Ophthalmol       Date:  1996-10       Impact factor: 5.258

6.  Management of submacular hemorrhage with intravitreous tissue plasminogen activator injection and pneumatic displacement.

Authors:  A S Hassan; M W Johnson; T E Schneiderman; C D Regillo; P E Tornambe; L S Poliner; B A Blodi; S G Elner
Journal:  Ophthalmology       Date:  1999-10       Impact factor: 12.079

7.  Factors prognostic of visual outcome in patients with subretinal hemorrhage.

Authors:  S R Bennett; J C Folk; C F Blodi; M Klugman
Journal:  Am J Ophthalmol       Date:  1990-01-15       Impact factor: 5.258

8.  Natural history of macular subretinal hemorrhage in age-related macular degeneration.

Authors:  A Scupola; G Coscas; G Soubrane; E Balestrazzi
Journal:  Ophthalmologica       Date:  1999       Impact factor: 3.250

9.  Tissue plasminogen activator treatment of experimental subretinal hemorrhage.

Authors:  H Lewis; S C Resnick; J G Flannery; B R Straatsma
Journal:  Am J Ophthalmol       Date:  1991-02-15       Impact factor: 5.258

10.  [Intravitreal injection of rt-PA and gas in the management of minor submacular haemorrhages secondary to age-related macular degeneration].

Authors:  Lars-Olof Hattenbach; Marion Brieden; Frank Koch; Hermann Gümbel
Journal:  Klin Monbl Augenheilkd       Date:  2002-07       Impact factor: 0.700

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