Daniel Adler1, Michel Millodot. 1. Department of Optometry, Hadassah College of Technology, Jerusalem, Israel.
Abstract
BACKGROUND:Undercorrection has recently been found to enhance the rate of progression of myopia. This result was thought to be controversial as it contrasted with expectations based on animal studies, as well as the results found wearing progressive addition lenses. The aim of the present study was to again determine the effect of undercorrection on the progression of myopia in a random population of children who are known to be very susceptible to myopia. METHODS: A cohort of 48 myopic children, aged six to 15 years was randomly assigned to either a fully corrected group (n = 23) or to an undercorrected group (n = 25). The subjects in the latter group were blurred by +0.50 D. The prospective study extended over a period of 18 months. Optometric examinations were carried out at the beginning of the study, then at six-month, 12-month and 18-month follow-up. RESULTS:Undercorrection produced a slight but not statistically significant increase in myopic progression over the 18-month period equal to 0.17 D, compared to full correction. A similar trend towards an increase in progression was noted in females and in children with near esophoria. CONCLUSION: This study supports the evidence that undercorrection does not represent an effective therapy to slow the rate of early-onset myopic progression, regardless of near heterophoria.
RCT Entities:
BACKGROUND: Undercorrection has recently been found to enhance the rate of progression of myopia. This result was thought to be controversial as it contrasted with expectations based on animal studies, as well as the results found wearing progressive addition lenses. The aim of the present study was to again determine the effect of undercorrection on the progression of myopia in a random population of children who are known to be very susceptible to myopia. METHODS: A cohort of 48 myopic children, aged six to 15 years was randomly assigned to either a fully corrected group (n = 23) or to an undercorrected group (n = 25). The subjects in the latter group were blurred by +0.50 D. The prospective study extended over a period of 18 months. Optometric examinations were carried out at the beginning of the study, then at six-month, 12-month and 18-month follow-up. RESULTS: Undercorrection produced a slight but not statistically significant increase in myopic progression over the 18-month period equal to 0.17 D, compared to full correction. A similar trend towards an increase in progression was noted in females and in children with near esophoria. CONCLUSION: This study supports the evidence that undercorrection does not represent an effective therapy to slow the rate of early-onset myopic progression, regardless of near heterophoria.
Authors: Jeffrey J Walline; Kristina Lindsley; Satyanarayana S Vedula; Susan A Cotter; Donald O Mutti; J Daniel Twelker Journal: Cochrane Database Syst Rev Date: 2011-12-07
Authors: Andrea Russo; Francesco Semeraro; Mario R Romano; Rodolfo Mastropasqua; Roberto Dell'Omo; Ciro Costagliola Journal: Int Ophthalmol Date: 2013-09-17 Impact factor: 2.031