Literature DB >> 16901651

Evidence for the link between healing time and the development of hypertrophic scars (HTS) in paediatric burns due to scald injury.

Tania C S Cubison1, Sarah A Pape, Nicholas Parkhouse.   

Abstract

The relationship between burn depth, healing time and the development of hypertrophic scarring (HTS) is well recognised by burn surgeons but is seldom mentioned in the published literature. We studied 337 children with scalds whose scars were monitored for up to 5 years. Overall HTS rates were found to be: under 10 days to healing=0%, 10-14 days=8%, 15-21 days=20%, 22-25 days=40%, 26-30 days=68% and over 30 days=92%. In the conservatively treated group the HTS rates are: under 10 days=0%, 10-14 days=2%, 15-21 days=20%, 22-25 days=28%, 26-30 days=75% and over 30 days=94%. If skin grafting is undertaken there is a much higher incidence of HTS in the 10-14 days group: 10-14 days=33%, 15-21 days=19%, 22-25 days=54%, 26-30 days=64% and over 30 days=88%. We conclude that there is a low risk of HTS formation in scalds healed before 21 days, and that surgery should be reserved for scalds likely to take more than 21 days to heal.

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Mesh:

Year:  2006        PMID: 16901651     DOI: 10.1016/j.burns.2006.02.007

Source DB:  PubMed          Journal:  Burns        ISSN: 0305-4179            Impact factor:   2.744


  48 in total

1.  [Surgical therapy of wounds and scars].

Authors:  J Koller
Journal:  Hautarzt       Date:  2013-08       Impact factor: 0.751

Review 2.  A review of tissue-engineered skin bioconstructs available for skin reconstruction.

Authors:  Rostislav V Shevchenko; Stuart L James; S Elizabeth James
Journal:  J R Soc Interface       Date:  2009-10-28       Impact factor: 4.118

3.  [Not Available].

Authors:  L Goffinet; A Breton; C Gavillot; S Barbary; P Journeau; P Lascombes; G Dautel
Journal:  Ann Burns Fire Disasters       Date:  2015-09-30

Review 4.  Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring.

Authors:  Meilang Xue; Christopher J Jackson
Journal:  Adv Wound Care (New Rochelle)       Date:  2015-03-01       Impact factor: 4.730

Review 5.  Scar management in burn injuries using drug delivery and molecular signaling: Current treatments and future directions.

Authors:  Saeid Amini-Nik; Yusef Yousuf; Marc G Jeschke
Journal:  Adv Drug Deliv Rev       Date:  2017-07-27       Impact factor: 15.470

6.  Scald management protocols - outcome differences in two different time periods using different treatment strategies.

Authors:  M Elmasry; I Steinvall; J Thorfinn; A H Abbas; O A Adly; I Abdelrahman; M A Nagi; F Sjoberg
Journal:  Ann Burns Fire Disasters       Date:  2016-06-30

Review 7.  Hypertrophic scarring: the greatest unmet challenge after burn injury.

Authors:  Celeste C Finnerty; Marc G Jeschke; Ludwik K Branski; Juan P Barret; Peter Dziewulski; David N Herndon
Journal:  Lancet       Date:  2016-10-01       Impact factor: 79.321

Review 8.  Hypertrophic Scarring: Current Knowledge of Predisposing Factors, Cellular and Molecular Mechanisms.

Authors:  Layla Nabai; Amir Pourghadiri; Aziz Ghahary
Journal:  J Burn Care Res       Date:  2020-01-30       Impact factor: 1.845

9.  A Prospective, Randomized, Controlled Trial Comparing the Outpatient Treatment of Pediatric and Adult Partial-Thickness Burns with Suprathel or Mepilex Ag.

Authors:  Gabriel Hundeshagen; Vanessa N Collins; Paul Wurzer; William Sherman; Charles D Voigt; Janos Cambiaso-Daniel; Omar Nunez Lopez; Jason Sheaffer; David N Herndon; Celeste C Finnerty; Ludwik K Branski
Journal:  J Burn Care Res       Date:  2018-02-20       Impact factor: 1.845

10.  Scar formation following excisional and burn injuries in a red Duroc pig model.

Authors:  Britani N Blackstone; Jayne Y Kim; Kevin L McFarland; Chandan K Sen; Dorothy M Supp; J Kevin Bailey; Heather M Powell
Journal:  Wound Repair Regen       Date:  2017-07-31       Impact factor: 3.617

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