Literature DB >> 31999336

Hypertrophic Scarring: Current Knowledge of Predisposing Factors, Cellular and Molecular Mechanisms.

Layla Nabai1, Amir Pourghadiri1, Aziz Ghahary1.   

Abstract

Hypertrophic scarring (HSc) is an age-old problem that still affects millions of people physically, psychologically, and economically. Despite advances in surgical techniques and wound care, prevention and treatment of HSc remains a challenge. Elucidation of factors involved in the development of this common fibroproliferative disorder is crucial for further progress in preventive and/or therapeutic measures. Our knowledge about pathophysiology of HSc at the cellular and molecular level has grown considerably in recent decades. In this article, current knowledge of predisposing factors and the cellular and molecular mechanisms of HSc has been reviewed. © American Burn Association 2020. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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Year:  2020        PMID： 31999336      PMCID： PMC6990447          DOI： 10.1093/jbcr/irz158

Source DB:  PubMed          Journal:  J Burn Care Res        ISSN： 1559-047X            Impact factor:   1.845


  78 in total

1.  Histopathological differential diagnosis of keloid and hypertrophic scar.

Authors:  Julia Yu-Yun Lee; Chao-Chun Yang; Sheau-Chiou Chao; Tak-Wah Wong
Journal:  Am J Dermatopathol       Date:  2004-10       Impact factor: 1.533

Review 2.  Prevalence of scar contractures after burn: A systematic review.

Authors:  Anouk M Oosterwijk; Leonora J Mouton; Hennie Schouten; Laurien M Disseldorp; Cees P van der Schans; Marianne K Nieuwenhuis
Journal:  Burns       Date:  2016-09-14       Impact factor: 2.744

3.  Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair.

Authors:  R Bucala; L A Spiegel; J Chesney; M Hogan; A Cerami
Journal:  Mol Med       Date:  1994-11       Impact factor: 6.354

4.  The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis.

Authors:  J S Munger; X Huang; H Kawakatsu; M J Griffiths; S L Dalton; J Wu; J F Pittet; N Kaminski; C Garat; M A Matthay; D B Rifkin; D Sheppard
Journal:  Cell       Date:  1999-02-05       Impact factor: 41.582

5.  Enhanced expression of mRNA for transforming growth factor-beta, type I and type III procollagen in human post-burn hypertrophic scar tissues.

Authors:  A Ghahary; Y J Shen; P G Scott; Y Gong; E E Tredget
Journal:  J Lab Clin Med       Date:  1993-10

6.  Alpha-MSH regulates interleukin-10 expression by human keratinocytes.

Authors:  P Redondo; J García-Foncillas; I Okroujnov; E Bandrés
Journal:  Arch Dermatol Res       Date:  1998-08       Impact factor: 3.017

7.  Human dermal fibroblast subpopulations; differential interactions with vascular endothelial cells in coculture: nonsoluble factors in the extracellular matrix influence interactions.

Authors:  J Michael Sorrell; Marilyn A Baber; Arnold I Caplan
Journal:  Wound Repair Regen       Date:  2008 Mar-Apr       Impact factor: 3.617

8.  Peripheral blood fibrocytes from burn patients: identification and quantification of fibrocytes in adherent cells cultured from peripheral blood mononuclear cells.

Authors:  Liju Yang; Paul G Scott; Jennifer Giuffre; Heather A Shankowsky; Aziz Ghahary; Edward E Tredget
Journal:  Lab Invest       Date:  2002-09       Impact factor: 5.662

9.  Adult Contractures in Burn Injury: A Burn Model System National Database Study.

Authors:  Jeremy Goverman; Katie Mathews; Richard Goldstein; Radha Holavanahalli; Karen Kowalske; Peter Esselman; Nicole Gibran; Oscar Suman; David Herndon; Colleen M Ryan; Jeffrey C Schneider
Journal:  J Burn Care Res       Date:  2017 Jan/Feb       Impact factor: 1.845

10.  Predicting severity of pathological scarring due to burn injuries: a clinical decision making tool using Bayesian networks.

Authors:  Paola Berchialla; Ezio Nicola Gangemi; Francesca Foltran; Arber Haxhiaj; Alessandra Buja; Fulvio Lazzarato; Maurizio Stella; Dario Gregori
Journal:  Int Wound J       Date:  2012-09-07       Impact factor: 3.315
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  3 in total

1.  Angiogenic gene characterization and vessel permeability of dermal microvascular endothelial cells isolated from burn hypertrophic scar.

Authors:  Esteban A Molina; Brandon Hartmann; Mary A Oliver; Liam D Kirkpatrick; John W Keyloun; Lauren T Moffatt; Jeffrey W Shupp; Taryn E Travis; Bonnie C Carney
Journal:  Sci Rep       Date:  2022-07-18       Impact factor: 4.996

2.  Effects of Apremilast on Induced Hypertrophic Scar of Rabbits.

Authors:  D Nidhal Ghazy; A Rahmah Abu-Raghif
Journal:  Arch Razi Inst       Date:  2021-12-30

Review 3.  A Scoping Review of the Methodology Used in Studies of Genetic Influences on the Development of Keloid or Hypertrophic Scarring in Adults and Children After Acute Wounding.

Authors:  Philippa Davies; Leila Cuttle; Amber Young
Journal:  Adv Wound Care (New Rochelle)       Date:  2021-07-14       Impact factor: 4.730
  3 in total

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