Literature DB >> 16897828

Metagenomics: an inexhaustible access to nature's diversity.

Martin Langer1, Esther M Gabor, Klaus Liebeton, Guido Meurer, Frank Niehaus, Renate Schulze, Jürgen Eck, Patrick Lorenz.   

Abstract

The chemical industry has an enormous need for innovation. To save resources, energy and time, currently more and more established chemical processes are being switched to biotechnological routes. This requires white biotechnology to discover and develop novel enzymes, biocatalysts and applications. Due to a limitation in the cultivability of microbes living in certain habitats, technologies have to be established which give access to the enormous resource of uncultivated microbial diversity. Metagenomics promises to provide new and diverse enzymes and biocatalysts as well as bioactive molecules and has the potential to make industrial biotechnology an economic, sustainable success.

Mesh:

Year:  2006        PMID: 16897828     DOI: 10.1002/biot.200600111

Source DB:  PubMed          Journal:  Biotechnol J        ISSN: 1860-6768            Impact factor:   4.677


  9 in total

1.  Nonlinear electrophoretic response yields a unique parameter for separation of biomolecules.

Authors:  Joel Pel; David Broemeling; Laura Mai; Hau-Ling Poon; Giorgia Tropini; René L Warren; Robert A Holt; Andre Marziali
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-17       Impact factor: 11.205

2.  Darwinian evolution in the light of genomics.

Authors:  Eugene V Koonin
Journal:  Nucleic Acids Res       Date:  2009-02-12       Impact factor: 16.971

Review 3.  Development of novel drugs from marine surface associated microorganisms.

Authors:  Anahit Penesyan; Staffan Kjelleberg; Suhelen Egan
Journal:  Mar Drugs       Date:  2010-03-01       Impact factor: 5.118

4.  Functional Screening of Hydrolytic Activities Reveals an Extremely Thermostable Cellulase from a Deep-Sea Archaeon.

Authors:  Benedikt Leis; Simon Heinze; Angel Angelov; Vu Thuy Trang Pham; Andrea Thürmer; Mohamed Jebbar; Peter N Golyshin; Wolfgang R Streit; Rolf Daniel; Wolfgang Liebl
Journal:  Front Bioeng Biotechnol       Date:  2015-07-01

5.  A metagenome-derived thermostable β-glucanase with an unusual module architecture which defines the new glycoside hydrolase family GH148.

Authors:  Angel Angelov; Vu Thuy Trang Pham; Maria Übelacker; Silja Brady; Benedikt Leis; Nicole Pill; Judith Brolle; Matthias Mechelke; Matthias Moerch; Bernard Henrissat; Wolfgang Liebl
Journal:  Sci Rep       Date:  2017-12-11       Impact factor: 4.379

6.  Relating destabilizing regions to known functional sites in proteins.

Authors:  Benoît H Dessailly; Marc F Lensink; Shoshana J Wodak
Journal:  BMC Bioinformatics       Date:  2007-04-30       Impact factor: 3.169

7.  Relevance of chemistry to white biotechnology.

Authors:  Munishwar N Gupta; Smita Raghava
Journal:  Chem Cent J       Date:  2007-06-20       Impact factor: 4.215

8.  Marine metagenomics: strategies for the discovery of novel enzymes with biotechnological applications from marine environments.

Authors:  Jonathan Kennedy; Julian R Marchesi; Alan Dw Dobson
Journal:  Microb Cell Fact       Date:  2008-08-21       Impact factor: 5.328

Review 9.  Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the "Supply Problem".

Authors:  Nelson G M Gomes; Ramesh Dasari; Sunena Chandra; Robert Kiss; Alexander Kornienko
Journal:  Mar Drugs       Date:  2016-05-21       Impact factor: 5.118

  9 in total

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