| Literature DB >> 1688644 |
J A Piccirilli1, T Krauch, S E Moroney, S A Benner.
Abstract
A new Watson-Crick base pair, with a hydrogen bonding pattern different from that in the A.T and G.C base pairs, is incorporated into duplex DNA and RNA by DNA and RNA polymerases and expands the genetic alphabet from 4 to 6 letters. This expansion could lead to RNAs with greater diversity in functional groups and greater catalytic potential.Entities:
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Year: 1990 PMID: 1688644 DOI: 10.1038/343033a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962