| Literature DB >> 16879972 |
Mari Sithambaram Karthikeyan1, Dasappa Jagadeesh Prasad, Boja Poojary, K Subrahmanya Bhat, Bantwal Shivarama Holla, Nalilu Suchetha Kumari.
Abstract
A series of 2,4-dichloro-5-fluorophenyl bearing Mannich base (4 and 5) was prepared from triazole Schiff bases (3) by aminomethylation with formaldehyde and secondary/substituted primary amines. All newly synthesized compounds were screened for their antimicrobial activity. Compounds 3c, 4c, 4e and 4f exhibited promising antibacterial and compounds 3c, 5c, 5e and 5f showed good antifungal activity.Entities:
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Year: 2006 PMID： 16879972 DOI： 10.1016/j.bmc.2006.07.015
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641