| Literature DB >> 16856806 |
Abstract
DNA helicases are found in all kingdoms of life and function in all DNA metabolic processes where the two strands of duplex DNA require to be separated. Here, we review recent developments in our understanding of the roles that helicases play in the intimately linked processes of replication fork repair and homologous recombination, and highlight how the cell has evolved many distinct, and sometimes antagonistic, uses for these enzymes.Mesh:
Substances:
Year: 2006 PMID: 16856806 DOI: 10.1146/annurev.genet.40.110405.090636
Source DB: PubMed Journal: Annu Rev Genet ISSN: 0066-4197 Impact factor: 16.830