| Literature DB >> 16841157 |
A A Andreev-Andrievskii1, D V Tsvirkun, E Yu Makarenko, L A Andreeva, A A Mart'yanov.
Abstract
Centrally administered doses of the tripeptide corticoliberin fragment CRF(4-6) (Pro-Pro-Ile) suppressed mating behavior in male rats. Doses of 1 and 2 microg of the tripeptide produced dose-dependent increases in the latent periods of mounting, intromission, and ejaculation. Changes in measures of sexual behavior demonstrated that the corticoliberin fragment CRF(4-6) suppressed both sexual motivation and sexual performance.Entities:
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Year: 2006 PMID： 16841157 DOI： 10.1007/s11055-006-0084-y
Source DB: PubMed Journal: Neurosci Behav Physiol ISSN： 0097-0549