| Literature DB >> 16825388 |
Magnus Lindh1, Charles Hannoun, Sebastian Malmström, Johan Lindberg, Gunnar Norkrans.
Abstract
The COBAS AMPLICOR hepatitis B virus assay targets a conserved region of the genome and is widely used to monitor treatment of hepatitis B in order to identify emerging resistance. However, the assay failed to recognize increasing viremia levels when YMDD mutations were paralleled by mutations in the segment targeted by the COBAS AMPLICOR probe.Entities:
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Year: 2006 PMID: 16825388 PMCID: PMC1489515 DOI: 10.1128/JCM.00265-06
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948