D Böhringer1, A Schindler, T Reinhard. 1. Augenklinik, Universitätsklinikum, Kilianstrasse 5, 79106, Freiburg. daniel.boehringer@uniklinik-freiburg.de
Abstract
BACKGROUND: Penetrating keratoplasty (PKP) is commonly referred to as the most successful transplantation procedure in medicine. This appraisal, however, is currently poorly supported by evidence. The aim of our study was to collect data on patient satisfaction with PKP as well as to analyze factors predisposing to dissatisfaction. PATIENTS AND METHODS: In the years 1988-2002 a total of 3,219 PKPs were performed on 2,981 patients. These patients were sent a questionnaire. The items pertained to subjective assessment of visual quality as compared to the situation before PKP and about regretting the PKP. RESULTS: The questionnaire was answered by 1,142 patients (59% of the traceable persons). The mean follow-up was 3.3+/-2.9 years. Indications for PKP were Fuchs' endothelial dystrophy (26%), keratoconus (23%), bullous keratopathy (15%), and further indications (36%). For these groups, best corrected visual acuity improved by more than two lines in 51, 80, 42, and 50%, respectively. The percentage of subjective improvement of vision was 73, 78, 47, and 63%. The percentage of regretting the PKP was 12, 4, 27, and 10%, respectively. All differences were highly statistically significant. Significant influencing factors on regretting the PKP were (inversely sorted for relevance): repeat graft failure, bullous keratopathy, contact lens wear, paresthesia, removal of running sutures, and patient age. CONCLUSIONS: General satisfaction with PKP is high. An important exception is bullous keratopathy, most likely due to accompanying morbidity (e.g., cystoid macular edema).
BACKGROUND: Penetrating keratoplasty (PKP) is commonly referred to as the most successful transplantation procedure in medicine. This appraisal, however, is currently poorly supported by evidence. The aim of our study was to collect data on patient satisfaction with PKP as well as to analyze factors predisposing to dissatisfaction. PATIENTS AND METHODS: In the years 1988-2002 a total of 3,219 PKPs were performed on 2,981 patients. These patients were sent a questionnaire. The items pertained to subjective assessment of visual quality as compared to the situation before PKP and about regretting the PKP. RESULTS: The questionnaire was answered by 1,142 patients (59% of the traceable persons). The mean follow-up was 3.3+/-2.9 years. Indications for PKP were Fuchs' endothelial dystrophy (26%), keratoconus (23%), bullous keratopathy (15%), and further indications (36%). For these groups, best corrected visual acuity improved by more than two lines in 51, 80, 42, and 50%, respectively. The percentage of subjective improvement of vision was 73, 78, 47, and 63%. The percentage of regretting the PKP was 12, 4, 27, and 10%, respectively. All differences were highly statistically significant. Significant influencing factors on regretting the PKP were (inversely sorted for relevance): repeat graft failure, bullous keratopathy, contact lens wear, paresthesia, removal of running sutures, and patient age. CONCLUSIONS: General satisfaction with PKP is high. An important exception is bullous keratopathy, most likely due to accompanying morbidity (e.g., cystoid macular edema).
Authors: Flavia Mendes; Debra A Schaumberg; Sam Navon; Roger Steinert; Joel Sugar; Edward J Holland; M Reza Dana Journal: Am J Ophthalmol Date: 2003-06 Impact factor: 5.258