Literature DB >> 16816945

The vertebral endplate: disc degeneration, disc regeneration.

Robert J Moore1.   

Abstract

The vertebral endplates are critical for maintaining disc function yet like other components of the disc are vulnerable to degeneration. This paper provides an overview of the development and normal function of the endplates as well as an impression of what happens when they undergo progressive degeneration. Recent research suggests that the degenerative process can be retarded or reversed.

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Year:  2006        PMID: 16816945      PMCID: PMC2335377          DOI: 10.1007/s00586-006-0170-4

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  54 in total

1.  Schmorl nodes of the thoracic and lumbar spine: radiographic-pathologic study of prevalence, characterization, and correlation with degenerative changes of 1,650 spinal levels in 100 cadavers.

Authors:  C W Pfirrmann; D Resnick
Journal:  Radiology       Date:  2001-05       Impact factor: 11.105

Review 2.  Cell-based therapy for disc repair.

Authors:  D Greg Anderson; Makarand V Risbud; Irving M Shapiro; Alexander R Vaccaro; Todd J Albert
Journal:  Spine J       Date:  2005 Nov-Dec       Impact factor: 4.166

Review 3.  Gene therapy for disc repair.

Authors:  Eric A Levicoff; Lars G Gilbertson; James D Kang
Journal:  Spine J       Date:  2005 Nov-Dec       Impact factor: 4.166

4.  Structural features and thickness of the vertebral cortex in the thoracolumbar spine.

Authors:  W T Edwards; Y Zheng; L A Ferrara; H A Yuan
Journal:  Spine (Phila Pa 1976)       Date:  2001-01-15       Impact factor: 3.468

5.  Elevated synthetic activity in the convex side of scoliotic intervertebral discs and endplates compared with normal tissues.

Authors:  J Antoniou; V Arlet; T Goswami; M Aebi; M Alini
Journal:  Spine (Phila Pa 1976)       Date:  2001-05-15       Impact factor: 3.468

6.  Premature vertebral endplate ossification and mild disc degeneration in mice after inactivation of one allele belonging to the Col2a1 gene for Type II collagen.

Authors:  J Sahlman; R Inkinen; T Hirvonen; M J Lammi; P E Lammi; J Nieminen; T Lapveteläinen; D J Prockop; M Arita; S W Li; M M Hyttinen; H J Helminen; K Puustjärvi
Journal:  Spine (Phila Pa 1976)       Date:  2001-12-01       Impact factor: 3.468

7.  Matrix metalloproteinases and aggrecanase: their role in disorders of the human intervertebral disc.

Authors:  S Roberts; B Caterson; J Menage; E H Evans; D C Jaffray; S M Eisenstein
Journal:  Spine (Phila Pa 1976)       Date:  2000-12-01       Impact factor: 3.468

8.  Exposure of the porcine spine to mechanical compression: differences in injury pattern between adolescents and adults.

Authors:  O Lundin; L Ekström; M Hellström; S Holm; L Swärd
Journal:  Eur Spine J       Date:  2000-12       Impact factor: 3.134

Review 9.  Gene therapy applications for intervertebral disc degeneration.

Authors:  Corey J Wallach; Lars G Gilbertson; James D Kang
Journal:  Spine (Phila Pa 1976)       Date:  2003-08-01       Impact factor: 3.468

10.  2002 SSE Award Competition in Basic Science: expression of major matrix metalloproteinases is associated with intervertebral disc degradation and resorption.

Authors:  C Weiler; A G Nerlich; J Zipperer; B E Bachmeier; N Boos
Journal:  Eur Spine J       Date:  2002-07-09       Impact factor: 3.134

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  56 in total

1.  Intervertebral disc development is regulated by Wnt/β-catenin signaling.

Authors:  Naoki Kondo; Takahito Yuasa; Kengo Shimono; Weien Tung; Takahiro Okabe; Rika Yasuhara; Maurizio Pacifici; Yejia Zhang; Masahiro Iwamoto; Motomi Enomoto-Iwamoto
Journal:  Spine (Phila Pa 1976)       Date:  2011-04-15       Impact factor: 3.468

Review 2.  Diversity of intervertebral disc cells: phenotype and function.

Authors:  Girish Pattappa; Zhen Li; Marianna Peroglio; Nadine Wismer; Mauro Alini; Sibylle Grad
Journal:  J Anat       Date:  2012-06-11       Impact factor: 2.610

3.  A morphological study of lumbar vertebral endplates: radiographic, visual and digital measurements.

Authors:  Yue Wang; Michele C Battié; Tapio Videman
Journal:  Eur Spine J       Date:  2012-06-29       Impact factor: 3.134

Review 4.  Diffusion-weighted imaging in musculoskeletal radiology-clinical applications and future directions.

Authors:  Nicholas Bhojwani; Peter Szpakowski; Sasan Partovi; Martin H Maurer; Ulrich Grosse; Hendrik von Tengg-Kobligk; Lisa Zipp-Partovi; Nathan Fergus; Christos Kosmas; Konstantin Nikolaou; Mark R Robbin
Journal:  Quant Imaging Med Surg       Date:  2015-10

5.  Classification of endplate lesions in the lumbar spine and association with risk factors, biochemistry, and genetics.

Authors:  Alessandra Colombini; Fabio Galbusera; Maria Cristina Cortese; Enrico Gallazzi; Marco Viganò; Domenico Albano; Sabina Cauci; Luca Maria Sconfienza; Marco Brayda-Bruno
Journal:  Eur Spine J       Date:  2021-01-16       Impact factor: 3.134

Review 6.  A survey of the "surgical and research" articles in the European Spine Journal, 2006.

Authors:  Robert C Mulholland
Journal:  Eur Spine J       Date:  2006-12-08       Impact factor: 3.134

7.  Injection of a polymerized hyaluronic acid/collagen hydrogel matrix in an in vivo porcine disc degeneration model.

Authors:  G W Omlor; A G Nerlich; H Lorenz; T Bruckner; W Richter; M Pfeiffer; T Gühring
Journal:  Eur Spine J       Date:  2012-04-25       Impact factor: 3.134

8.  A phased rehabilitation protocol for athletes with lumbar intervertebral disc herniation.

Authors:  Leonard H Vangelder; Barbara J Hoogenboom; Daniel W Vaughn
Journal:  Int J Sports Phys Ther       Date:  2013-08

9.  Characterization of the annulus fibrosus-vertebral body interface: identification of new structural features.

Authors:  Y S Nosikova; J P Santerre; M Grynpas; G Gibson; R A Kandel
Journal:  J Anat       Date:  2012-07-03       Impact factor: 2.610

10.  Terminal complement complex formation is associated with intervertebral disc degeneration.

Authors:  Graciosa Q Teixeira; Zhiyao Yong; Raquel M Goncalves; Amelie Kuhn; Jana Riegger; Helena Brisby; Helena Barreto Henriksson; Michael Ruf; Andreas Nerlich; Uwe M Mauer; Anita Ignatius; Rolf E Brenner; Cornelia Neidlinger-Wilke
Journal:  Eur Spine J       Date:  2020-09-16       Impact factor: 3.134

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