| Literature DB >> 16815382 |
Abstract
There are many reasons why the dietary-heart-cholesterol hypothesis should be questioned, and why statins might be acting in some other way to reduce the risk of coronary heart disease. Here, I propose that rather than being cholesterol-lowering drugs per se, statins act as vitamin D analogues, and explain why. This proposition is based on published observations that the unexpected and unexplained clinical benefits produced by statins have also been shown to be properties of vitamin D. It seems likely that statins activate vitamin D receptors.Entities:
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Year: 2006 PMID: 16815382 DOI: 10.1016/S0140-6736(06)68971-X
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321