Literature DB >> 168118

Watery diarrhea associated with pancreatic islet cell carcinoma.

M G Schmitt, K H Soergel, G T Hensley, W Y Chey.   

Abstract

A patient with severe watery diarrhea and a non-beta islet cell carcinoma of the pancreas producing five hormones (secretin, serotonin, enteroglucagon, vasoactive intestinal polypeptide, and pancreatic glucagon) is described. We have demonstrated massive pancreatic hypersecretion to be a major factor in this patient's diarrhea. Possible inter-relationships of the actions of five hormones present in excess in the patient are discussed.

Entities:  

Mesh：

Substances：

Year:  1975        PMID： 168118

Source DB:  PubMed          Journal:  Gastroenterology        ISSN： 0016-5085            Impact factor:   22.682


  8 in total

1.  Watery diarrhea syndrome. Two unusual cases and further evidence that VIP is a humoral mediator.

Authors:  A M Cooperman; D Desantis; E Winkelman; R Farmer; J Eversman; S Said
Journal:  Ann Surg       Date:  1978-03       Impact factor: 12.969

2.  Effects of vasoactive intestinal peptide and pancreatic polypeptide in rabbit intestine.

Authors:  M Camilleri; B T Cooper; T E Adrian; S R Bloom; V S Chadwick
Journal:  Gut       Date:  1981-01       Impact factor: 23.059

3.  Primary Pancreatic Secretinoma: Further Evidence Supporting Secretin as a Diarrheogenic Hormone.

Authors:  William Y Chey; Wendy L Frankel; Sashwati Roy; Soma Datta; Chandan K Sen; Mary Dillhoff; Peter Muscarella; Konrad H Soergel; Ronald K Tompkins; Ta-Min Chang; Edward L Bradley; Edwin Christopher Ellison
Journal:  Ann Surg       Date:  2017-08       Impact factor: 12.969

4.  Vasoative intestinal peptide and the watery diarrhea syndrome.

Authors:  A M Ebeid; P D Murray; J E Fischer
Journal:  Ann Surg       Date:  1978-04       Impact factor: 12.969

5.  Prostaglandins E and F in endocrine diarrheagenic syndromes.

Authors:  B M Jaffe; S Condon
Journal:  Ann Surg       Date:  1976-10       Impact factor: 12.969

Review 6.  Prostaglandins and serotonin: nonpeptide diarrheogenic hormones.

Authors:  B M Jaffe
Journal:  World J Surg       Date:  1979-09-20       Impact factor: 3.352

7.  Mixed pancreatic apudoma with symptoms of excess vasoactive intestinal polypeptide and insulin: improvement of diarrhoea with metoclopramide.

Authors:  R G Long; M G Bryant; P M Yuille; J M Polak; S R Bloom
Journal:  Gut       Date:  1981-06       Impact factor: 23.059

8.  Intractable diarrhea. Intestinal perfusion studies and plasma VIP concentrations in patients with pancreatic cholera syndrome and surreptitious ingestion of laxatives and diuretics.

Authors:  G J Krejs; J H Walsh; S G Morawski; J S Fordtran
Journal:  Am J Dig Dis       Date:  1977-04
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.