Literature DB >> 16790395

Quality of Life assessment through the EORTC questionnaires of locally advanced rectal cancer patients treated with preoperative chemo-radiotherapy.

Juan Ignacio Arraras Urdaniz1, Fernando Arias de la Vega, Ruth Vera García, Ana Manterola Burgaleta, Maite Martínez Aguillo, Elena Villafranca Iturre, Esteban Salgado Pascual.   

Abstract

PURPOSE: To assess the quality of life in a group of rectal cancer patients during the treatment period.
MATERIAL AND METHODS: A sample of 83 rectal cancer patients in Dukes' stages B2 or C who started a chemoradiotherapy treatment followed by surgery, have filled in the EORTC core questionnaire QLQC30 and the colorectal module QLQ-CR38, in three moments during the treatment and follow-up periods: at the beginning of the treatment, at the end of the chemoradiotherapy, and after surgery. Clinical and demographic data have also been recorded. Quality of Life scores and changes in them among the three assessments have been calculated.
RESULTS: Quality of life scores of patients who have followed the treatment has been good in most dimensions, and has shown similar to the clinical data. Soft and moderate alterations have appeared in the areas of disease symptoms, treatment toxicity, fatigue, emotional and sexual functioning, and also in functional areas after surgery. Quality of life has been stable or has had small changes in most dimensions. A worsening in toxicity areas has appeared after the neoadyuvant treatment. After surgery there has been a worsening in functional areas, fatigue and appetite loss, and an improvement in diarrhoea.
CONCLUSIONS: Quality of life scores and clinical data indicate that the situation of the patients who have received the treatments has been good. Patients under treatment stood it adequately.

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Year:  2006        PMID: 16790395     DOI: 10.1007/s12094-006-0196-4

Source DB:  PubMed          Journal:  Clin Transl Oncol        ISSN: 1699-048X            Impact factor:   3.405


  20 in total

1.  The construction and testing of the EORTC colorectal cancer-specific quality of life questionnaire module (QLQ-CR38). European Organization for Research and Treatment of Cancer Study Group on Quality of Life.

Authors:  M A Sprangers; A te Velde; N K Aaronson
Journal:  Eur J Cancer       Date:  1999-02       Impact factor: 9.162

2.  Quality of life in patients with urinary diversion after operation for locally advanced rectal cancer.

Authors:  M G Guren; J N Wiig; S Dueland; K M Tveit; S D Fosså; H Waehre; K E Giercksky
Journal:  Eur J Surg Oncol       Date:  2001-11       Impact factor: 4.424

3.  The impact of recurrent rectal cancer on quality of life.

Authors:  J Camilleri-Brennan; R J Steele
Journal:  Eur J Surg Oncol       Date:  2001-06       Impact factor: 4.424

4.  Adjuvant versus neoadjuvant radiochemotherapy for locally advanced rectal cancer. A progress report of a phase-III randomized trial (protocol CAO/ARO/AIO-94).

Authors:  R Sauer; R Fietkau; C Wittekind; P Martus; C Rödel; W Hohenberger; G Jatzko; H Sabitzer; J H Karstens; H Becker; C Hess; R Raab
Journal:  Strahlenther Onkol       Date:  2001-04       Impact factor: 3.621

5.  Assessment of quality of life in patients with rectal cancer treated by preoperative radiotherapy: a longitudinal prospective study.

Authors:  Abdelkarim S Allal; Pascal Gervaz; Philippe Gertsch; Jacques Bernier; Arnaud D Roth; Philippe Morel; Sabine Bieri
Journal:  Int J Radiat Oncol Biol Phys       Date:  2005-03-15       Impact factor: 7.038

Review 6.  Evaluation of quality of life after laparoscopic surgery: evidence-based guidelines of the European Association for Endoscopic Surgery.

Authors:  D Korolija; S Sauerland; S Wood-Dauphinée; C C Abbou; E Eypasch; M García Caballero; M A Lumsden; B Millat; J R T Monson; G Nilsson; R Pointner; W Schwenk; A Shamiyeh; A Szold; E Targarona; B Ure; E Neugebauer
Journal:  Surg Endosc       Date:  2004-04-27       Impact factor: 4.584

7.  The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology.

Authors:  N K Aaronson; S Ahmedzai; B Bergman; M Bullinger; A Cull; N J Duez; A Filiberti; H Flechtner; S B Fleishman; J C de Haes
Journal:  J Natl Cancer Inst       Date:  1993-03-03       Impact factor: 13.506

8.  Adjuvant vs. neoadjuvant radiochemotherapy for locally advanced rectal cancer: the German trial CAO/ARO/AIO-94.

Authors:  R Sauer; R Fietkau; C Wittekind; C Rödel; P Martus; W Hohenberger; J Tschmelitsch; H Sabitzer; J-H Karstens; H Becker; C Hess; R Raab
Journal:  Colorectal Dis       Date:  2003-09       Impact factor: 3.788

9.  Randomized clinical trial comparing quality of life after straight and pouch coloanal reconstruction.

Authors:  M Sailer; K-H Fuchs; M Fein; A Thiede
Journal:  Br J Surg       Date:  2002-09       Impact factor: 6.939

10.  Preoperative concomitant radiotherapy and chemotherapy in ultrasound-staged T3 and T4 rectal cancer.

Authors:  Gabriele Luppi; Mario Santantonio; Federica Bertolini; Francesco Fiorica; Francesca Zanelli; Margherita Gavioli; Mario Balli; Vittorio Silingardi
Journal:  Tumori       Date:  2003 Mar-Apr
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  7 in total

1.  The EORTC Quality of Life questionnaire for patients with colorectal cancer: EORTC QLQ-CR29 validation study for Spanish patients.

Authors:  Juan Ignacio Arraras; Javier Suárez; Fernando Arias de la Vega; Ruth Vera; Gemma Asín; Virginia Arrazubi; Mikel Rico; Lucía Teijeira; Jaione Azparren
Journal:  Clin Transl Oncol       Date:  2011-01       Impact factor: 3.405

2.  Non-inferiority multicenter prospective randomized controlled study of rectal cancer T2-T3s (superficial) N0, M0 undergoing neoadjuvant treatment and local excision (TEM) vs total mesorectal excision (TME).

Authors:  X Serra-Aracil; C Pericay; T Golda; L Mora; E Targarona; S Delgado; A Reina; F Vallribera; J M Enriquez-Navascues; S Serra-Pla; J C Garcia-Pacheco
Journal:  Int J Colorectal Dis       Date:  2017-12-12       Impact factor: 2.571

3.  A Prospective Study Evaluating Health-Related Quality of Life Following a Multimodal Treatment for Colorectal Cancer.

Authors:  Maria Perrone; Carlo Garufi; Maurizio Cosimelli; Franco Graziano; Chiara Falcicchio; Alessandro Bonucci; Luana Fotia; Diana Giannarelli; Luca Giacomelli; Gennaro Ciliberto; Patrizia Pugliese
Journal:  J Gastrointest Cancer       Date:  2022-01-24

Review 4.  Systematic Review of Cognitive Impairment in Colorectal Cancer Survivors Who Received Chemotherapy.

Authors:  Ya-Ning Chan; Ashley Leak Bryant; Jamie L Conklin; Tyra Girdwood; Aaron Piepmeier; Rachel Hirschey
Journal:  Oncol Nurs Forum       Date:  2021-11-01       Impact factor: 2.172

5.  The EORTC Quality of Life Questionnaire for patients with prostate cancer: EORTC QLQ-PR25. Validation study for Spanish patients.

Authors:  J I Arraras; E Villafranca; F Arias de la Vega; P Romero; M Rico; M Vila; G Asín; V Chicata; M A Domínguez; N Lainez; A Manterola; E Martínez; M Martínez
Journal:  Clin Transl Oncol       Date:  2009-03       Impact factor: 3.405

6.  Validation of the chinese version of the EORTC QLQ-CR29 in patients with colorectal cancer.

Authors:  Jin-Bo Lin; Lei Zhang; Dong-Wen Wu; Zhou-Huan Xi; Xue-Jun Wang; Yun-Shou Lin; Wakana Fujiwara; Jing-Ru Tian; Min Wang; Peng Peng; Ai Guo; Zhen Yang; Le Luo; Ling-Ya Jiang; Qia-Qia Li; Xue-Ying Zhang; Yun-Feng Zhang; Hou-Wei Xu; Bing Yang; Xun-Lin Li; Yi-Xiong Lei
Journal:  World J Gastroenterol       Date:  2017-03-14       Impact factor: 5.742

7.  Validation of the Danish version of the disease specific instrument EORTC QLQ-CR38 to assess health-related quality of life in patients with colorectal cancer.

Authors:  Henriette Vind Thaysen; P Jess; Søren Laurberg; M Groenvold
Journal:  Health Qual Life Outcomes       Date:  2012-12-14       Impact factor: 3.186

  7 in total

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