Literature DB >> 16770449

Exposure to a specific pulsed low-frequency magnetic field: a double-blind placebo-controlled study of effects on pain ratings in rheumatoid arthritis and fibromyalgia patients.

N M Shupak1, Julia C McKay, Warren R Nielson, Gary B Rollman, Frank S Prato, Alex W Thomas.   

Abstract

BACKGROUND: Specific pulsed electromagnetic fields (PEMFs) have been shown to induce analgesia (antinociception) in snails, rodents and healthy human volunteers.
OBJECTIVE: The effect of specific PEMF exposure on pain and anxiety ratings was investigated in two patient populations.
DESIGN: A double-blind, randomized, placebo-controlled parallel design was used.
METHOD: The present study investigated the effects of an acute 30 min magnetic field exposure (less than or equal to 400 microTpk; less than 3 kHz) on pain (McGill Pain Questionnaire [MPQ], visual analogue scale [VAS]) and anxiety (VAS) ratings in female rheumatoid arthritis (RA) (n=13; mean age 52 years) and fibromyalgia (FM) patients (n=18; mean age 51 years) who received either the PEMF or sham exposure treatment.
RESULTS: A repeated measures analysis revealed a significant pre-post-testing by condition interaction for the MPQ Pain Rating Index total for the RA patients, F(1,11)=5.09, P<0.05, estimate of effect size = 0.32, power = 0.54. A significant pre-post-effect for the same variable was present for the FM patients, F(1,15)=16.2, P<0.01, estimate of effect size = 0.52, power =0.96. Similar findings were found for MPQ subcomponents and the VAS (pain). There was no significant reduction in VAS anxiety ratings pre- to post-exposure for either the RA or FM patients.
CONCLUSION: These findings provide some initial support for the use of PEMF exposure in reducing pain in chronic pain populations and warrants continued investigation into the use of PEMF exposure for short-term pain relief.

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Year:  2006        PMID: 16770449      PMCID: PMC2585480          DOI: 10.1155/2006/842162

Source DB:  PubMed          Journal:  Pain Res Manag        ISSN: 1203-6765            Impact factor:   3.037


  19 in total

1.  Resting EEG is affected by exposure to a pulsed ELF magnetic field.

Authors:  Charles M Cook; Alex W Thomas; Frank S Prato
Journal:  Bioelectromagnetics       Date:  2004-04       Impact factor: 2.010

2.  Antinociceptive effects of a pulsed magnetic field in the land snail, Cepaea nemoralis.

Authors:  A W Thomas; M Kavaliers; F S Prato; K P Ossenkopp
Journal:  Neurosci Lett       Date:  1997-01-31       Impact factor: 3.046

3.  Human magnetoreception for navigation.

Authors:  R R Baker
Journal:  Prog Clin Biol Res       Date:  1988

4.  Day-night rhythms of opioid and non-opioid stress-induced analgesia: differential inhibitory effects of exposure to magnetic fields.

Authors:  Martin Kavaliers; Klaus-Peter Ossenkopp
Journal:  Pain       Date:  1988-02       Impact factor: 6.961

5.  The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis.

Authors:  F C Arnett; S M Edworthy; D A Bloch; D J McShane; J F Fries; N S Cooper; L A Healey; S R Kaplan; M H Liang; H S Luthra
Journal:  Arthritis Rheum       Date:  1988-03

Review 6.  Human electrophysiological and cognitive effects of exposure to ELF magnetic and ELF modulated RF and microwave fields: a review of recent studies.

Authors:  C M Cook; A W Thomas; F S Prato
Journal:  Bioelectromagnetics       Date:  2002-02       Impact factor: 2.010

7.  Human exposure to a specific pulsed magnetic field: effects on thermal sensory and pain thresholds.

Authors:  Naomi M Shupak; Frank S Prato; Alex W Thomas
Journal:  Neurosci Lett       Date:  2004-06-10       Impact factor: 3.046

8.  The validation of visual analogue scales as ratio scale measures for chronic and experimental pain.

Authors:  Donald D Price; Patricia A McGrath; Amir Rafii; Barbara Buckingham
Journal:  Pain       Date:  1983-09       Impact factor: 6.961

9.  Low-field magnetic stimulation in bipolar depression using an MRI-based stimulator.

Authors:  Michael Rohan; Aimee Parow; Andrew L Stoll; Christina Demopulos; Seth Friedman; Stephen Dager; John Hennen; Bruce M Cohen; Perry F Renshaw
Journal:  Am J Psychiatry       Date:  2004-01       Impact factor: 18.112

10.  The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee.

Authors:  F Wolfe; H A Smythe; M B Yunus; R M Bennett; C Bombardier; D L Goldenberg; P Tugwell; S M Campbell; M Abeles; P Clark
Journal:  Arthritis Rheum       Date:  1990-02
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  15 in total

Review 1.  [Physiotherapy and physical therapies for fibromyalgia syndrome. Systematic review, meta-analysis and guideline].

Authors:  A Winkelmann; W Häuser; E Friedel; M Moog-Egan; D Seeger; M Settan; T Weiss; M Schiltenwolf
Journal:  Schmerz       Date:  2012-06       Impact factor: 1.107

2.  Short-term effects of pulsed electromagnetic fields after physical exercise are dependent on autonomic tone before exposure.

Authors:  V Grote; H Lackner; C Kelz; M Trapp; F Aichinger; H Puff; M Moser
Journal:  Eur J Appl Physiol       Date:  2007-08-03       Impact factor: 3.078

3.  A randomized, double-blind, placebo-controlled clinical trial using a low-frequency magnetic field in the treatment of musculoskeletal chronic pain.

Authors:  Alex W Thomas; Karissa Graham; Frank S Prato; Julia McKay; Patricia Morley Forster; Dwight E Moulin; Sesh Chari
Journal:  Pain Res Manag       Date:  2007       Impact factor: 3.037

4.  [Physiotherapy, exercise and strength training and physical therapies in the treatment of fibromyalgia syndrome].

Authors:  M Schiltenwolf; W Häuser; E Felde; C Flügge; R Häfner; M Settan; M Offenbächer
Journal:  Schmerz       Date:  2008-06       Impact factor: 1.107

Review 5.  [Medical relevance of magnetic fields in pain therapy].

Authors:  G Salomonowitz; M Friedrich; B J Güntert
Journal:  Schmerz       Date:  2011-04       Impact factor: 1.107

Review 6.  New approaches for treating atrial fibrillation: Focus on autonomic modulation.

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Journal:  Trends Cardiovasc Med       Date:  2019-10-31       Impact factor: 6.677

7.  Chiropractic management of a patient with persistent headache.

Authors:  Jason West; Reed B Phillips
Journal:  J Chiropr Med       Date:  2013-12

Review 8.  Electromagnetic therapy for treating venous leg ulcers.

Authors:  Zoriah Aziz; Nicky Cullum
Journal:  Cochrane Database Syst Rev       Date:  2015-07-02

Review 9.  Electromagnetic therapy for treating pressure ulcers.

Authors:  Zoriah Aziz; Sally E M Bell-Syer
Journal:  Cochrane Database Syst Rev       Date:  2015-09-03

10.  Reduction of pain thresholds in fibromyalgia after very low-intensity magnetic stimulation: a double-blinded, randomized placebo-controlled clinical trial.

Authors:  Ceferino Maestú; Manuel Blanco; Angel Nevado; Julia Romero; Patricia Rodríguez-Rubio; Javier Galindo; Juan Bautista Lorite; Francisco de las Morenas; Pedro Fernández-Argüelles
Journal:  Pain Res Manag       Date:  2013 Nov-Dec       Impact factor: 3.037

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