PURPOSE: To introduce and examine the utility of a retinal imaging technique using high-speed optical coherence tomography (OCT) for creating a more complete retinal structural map to aid in the evaluation of patients with macular pathology. DESIGN: Prospective observational case series. PARTICIPANTS: Five patients with a variety of macular pathologies. METHODS: Patients were imaged with a Fourier-domain high-speed high-resolution OCT system built at our institution. A sweeping serial OCT B-scan of the macula was acquired to create a detailed retinal structural map. The data were then used to make individual clinical observations. RESULTS: Rapid serial OCT B-scans produced detailed macular maps for all 5 patients. Diagnoses of imaged patients included macular hole, lamellar macular hole, regressed macular hole or macular microhole, choroidal neovascular membrane (CNV) from age-related macular degeneration, and CNV from presumed ocular histoplasmosis syndrome. Reconstructed B-scans and C-scans are shown for selected patients to illustrate the additional perspectives gained by obtaining a detailed retinal map. CONCLUSIONS: Rapid serial Fourier-domain OCT B-scanning can be used to create a detailed retinal structural map. This technique provides additional information that can be missed on single OCT images and provides an accurate way to image large or complex lesions, and allows B-scan and C-scan reconstructions to be made that provide additional perspectives into retinal structures that may be missed using traditional imaging methods.
PURPOSE: To introduce and examine the utility of a retinal imaging technique using high-speed optical coherence tomography (OCT) for creating a more complete retinal structural map to aid in the evaluation of patients with macular pathology. DESIGN: Prospective observational case series. PARTICIPANTS: Five patients with a variety of macular pathologies. METHODS:Patients were imaged with a Fourier-domain high-speed high-resolution OCT system built at our institution. A sweeping serial OCT B-scan of the macula was acquired to create a detailed retinal structural map. The data were then used to make individual clinical observations. RESULTS: Rapid serial OCT B-scans produced detailed macular maps for all 5 patients. Diagnoses of imaged patients included macular hole, lamellar macular hole, regressed macular hole or macular microhole, choroidal neovascular membrane (CNV) from age-related macular degeneration, and CNV from presumed ocular histoplasmosis syndrome. Reconstructed B-scans and C-scans are shown for selected patients to illustrate the additional perspectives gained by obtaining a detailed retinal map. CONCLUSIONS: Rapid serial Fourier-domain OCT B-scanning can be used to create a detailed retinal structural map. This technique provides additional information that can be missed on single OCT images and provides an accurate way to image large or complex lesions, and allows B-scan and C-scan reconstructions to be made that provide additional perspectives into retinal structures that may be missed using traditional imaging methods.
Authors: Adrian Gh Podoleanu; George M Dobre; Radu G Cucu; Richard Rosen; Patricia Garcia; Juan Nieto; Daniel Will; Ronald Gentile; Thomas Muldoon; Joseph Walsh; Lawrence A Yannuzzi; Yale Fisher; Dennis Orlock; Rishard Weitz; John A Rogers; Shane Dunne; Aaron Boxer Journal: J Biomed Opt Date: 2004 Jan-Feb Impact factor: 3.170
Authors: Maciej Wojtkowski; Rainer Leitgeb; Andrzej Kowalczyk; Tomasz Bajraszewski; Adolf F Fercher Journal: J Biomed Opt Date: 2002-07 Impact factor: 3.170
Authors: Maciej Wojtkowski; Tomasz Bajraszewski; Iwona Gorczyńska; Piotr Targowski; Andrzej Kowalczyk; Wojciech Wasilewski; Czesław Radzewicz Journal: Am J Ophthalmol Date: 2004-09 Impact factor: 5.258
Authors: Hans E Grossniklaus; Päivi H Miskala; W Richard Green; Susan B Bressler; Barbara S Hawkins; Cynthia Toth; David J Wilson; Neil M Bressler Journal: Arch Ophthalmol Date: 2005-07
Authors: Maciej Wojtkowski; Vivek Srinivasan; Tony Ko; James Fujimoto; Andrzej Kowalczyk; Jay Duker Journal: Opt Express Date: 2004-05-31 Impact factor: 3.894
Authors: D Huang; E A Swanson; C P Lin; J S Schuman; W G Stinson; W Chang; M R Hee; T Flotte; K Gregory; C A Puliafito Journal: Science Date: 1991-11-22 Impact factor: 47.728
Authors: Gadi Wollstein; Leila A Paunescu; Tony H Ko; James G Fujimoto; Andrew Kowalevicz; Ingmar Hartl; Siobahn Beaton; Hiroshi Ishikawa; Cynthia Mattox; Omah Singh; Jay Duker; Wolfgang Drexler; Joel S Schuman Journal: Ophthalmology Date: 2005-02 Impact factor: 12.079
Authors: Eric K Chin; Rupan Trikha; Lawrence S Morse; Robert J Zawadzki; John S Werner; Susanna S Park Journal: Ophthalmic Surg Lasers Imaging Date: 2010-03-09
Authors: David G Telander; Stacey S Choi; Robert J Zawadzki; Neal Berger; John L Keltner; John S Werner Journal: Ophthalmic Surg Lasers Imaging Date: 2010-03-09
Authors: Hiroshi Ishikawa; Jongsick Kim; Thomas R Friberg; Gadi Wollstein; Larry Kagemann; Michelle L Gabriele; Kelly A Townsend; Kyung R Sung; Jay S Duker; James G Fujimoto; Joel S Schuman Journal: Invest Ophthalmol Vis Sci Date: 2008-10-24 Impact factor: 4.799