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Literature DB >> 16740965

DNA binding by the Methanothermobacter thermautotrophicus Cdc6 protein is inhibited by the minichromosome maintenance helicase.

Rajesh Kasiviswanathan¹, Jae-Ho Shin, Zvi Kelman.

Abstract

The Cdc6 proteins from the archaeon Methanothermobacter thermautotrophicus were previously shown to bind double-stranded DNA. It is shown here that the proteins also bind single-stranded DNA. Using minichromosome maintenance (MCM) helicase mutant proteins unable to bind DNA, it was found that the interaction of MCM with Cdc6 inhibits the DNA binding activity of Cdc6.

Entities: Gene Species

Mesh：

Substances：

Year: 2006 PMID： 16740965 PMCID： PMC1482948 DOI： 10.1128/JB.00168-06

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

17 in total

1. The zinc finger domain of the archaeal minichromosome maintenance protein is required for helicase activity.

Authors: A Poplawski; B Grabowski; S E Long; Z Kelman
Journal: J Biol Chem Date: 2001-10-17 Impact factor: 5.157

Review 2. DNA replication in eukaryotic cells.

Authors: Stephen P Bell; Anindya Dutta
Journal: Annu Rev Biochem Date: 2001-11-09 Impact factor: 23.643

Review 3. Common domains in the initiators of DNA replication in Bacteria, Archaea and Eukarya: combined structural, functional and phylogenetic perspectives.

Authors: Rafael Giraldo
Journal: FEMS Microbiol Rev Date: 2003-01 Impact factor: 16.408

4. Regulation of minichromosome maintenance helicase activity by Cdc6.

Authors: Jae-Ho Shin; Beatrice Grabowski; Rajesh Kasiviswanathan; Stephen D Bell; Zvi Kelman
Journal: J Biol Chem Date: 2003-07-01 Impact factor: 5.157

Review 5. Archaea: an archetype for replication initiation studies?

Authors: Lori M Kelman; Zvi Kelman
Journal: Mol Microbiol Date: 2003-05 Impact factor: 3.501

Review 6. Archaeal DNA replication and repair.

Authors: Zvi Kelman; Malcolm F White
Journal: Curr Opin Microbiol Date: 2005-10-20 Impact factor: 7.934

7. Autophosphorylation of archaeal Cdc6 homologues is regulated by DNA.

Authors: B Grabowski; Z Kelman
Journal: J Bacteriol Date: 2001-09 Impact factor: 3.490

8. Bacterial mode of replication with eukaryotic-like machinery in a hyperthermophilic archaeon.

Authors: H Myllykallio; P Lopez; P López-García; R Heilig; W Saurin; Y Zivanovic; H Philippe; P Forterre
Journal: Science Date: 2000-06-23 Impact factor: 47.728

9. The structure and function of MCM from archaeal M. Thermoautotrophicum.

Authors: Ryan J Fletcher; Brooke E Bishop; Ronald P Leon; Robert A Sclafani; Craig M Ogata; Xiaojiang S Chen
Journal: Nat Struct Biol Date: 2003-03

Review 10. Replicative helicase loaders: ring breakers and ring makers.

Authors: Megan J Davey; Mike O'Donnell
Journal: Curr Biol Date: 2003-08-05 Impact factor: 10.834

6 in total

1. Mutational analysis of conserved aspartic acid residues in the Methanothermobacter thermautotrophicus MCM helicase.

Authors: Nozomi Sakakibara; Rajesh Kasiviswanathan; Zvi Kelman
Journal: Extremophiles Date: 2011-01-28 Impact factor: 2.395

2. The Methanothermobacter thermautotrophicus Cdc6-2 protein, the putative helicase loader, dissociates the minichromosome maintenance helicase.

Authors: Jae-Ho Shin; Gun Young Heo; Zvi Kelman
Journal: J Bacteriol Date: 2008-04-04 Impact factor: 3.490