Literature DB >> 167279

Pleiotropic effects of a DNA adenine methylation mutation (dam-3) in Escherichia coli K12.

M G Marinus, N R Morris.   

Abstract

The dam-3 mutation results in a five-fold reduction in the number of 6-methyl-adenine (6-meA) residues in the DNA of E. coli K12 or phage lambda. The DNA of phage fd appears to be devoid of 6-meA when propagated on dam-3 bacteria. The phenotypic differences between dam-3 and dam+ bacteria include: (i) increased free phage in lysogenic dam-3 cultures, (2) increased sensitivity to methyl methanesulfonate (MMS), (3) inviability of dam-3 lex-I strains, (4) lower molecular weight of DNA in dam-3 bacteria in the absence of DNA ligase and (5) increased rate of DNA degradation in dam-3 recA strains.

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Year:  1975        PMID： 167279     DOI： 10.1016/0027-5107(75)90309-7

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  88 in total

1.  Recombination is essential for viability of an Escherichia coli dam (DNA adenine methyltransferase) mutant.

Authors:  M G Marinus
Journal:  J Bacteriol       Date:  2000-01       Impact factor: 3.490

2.  Saturation of mismatch repair in the mutD5 mutator strain of Escherichia coli.

Authors:  V Damagnez; M P Doutriaux; M Radman
Journal:  J Bacteriol       Date:  1989-08       Impact factor: 3.490

3.  Methyltransferase DnmA is responsible for genome-wide N6-methyladenosine modifications at non-palindromic recognition sites in Bacillus subtilis.

Authors:  Taylor M Nye; Lieke A van Gijtenbeek; Amanda G Stevens; Jeremy W Schroeder; Justin R Randall; Lindsay A Matthews; Lyle A Simmons
Journal:  Nucleic Acids Res       Date:  2020-06-04       Impact factor: 16.971

4.  Factors determining the frequency of plasmid cointegrate formation mediated by insertion sequence IS3 from Escherichia coli.

Authors:  J Spielmann-Ryser; M Moser; P Kast; H Weber
Journal:  Mol Gen Genet       Date:  1991-05

5.  Dam methyltransferase is required for stable lysogeny of the Shiga toxin (Stx2)-encoding bacteriophage 933W of enterohemorrhagic Escherichia coli O157:H7.

Authors:  Kenan C Murphy; Jennifer M Ritchie; Matthew K Waldor; Anders Løbner-Olesen; M G Marinus
Journal:  J Bacteriol       Date:  2007-11-02       Impact factor: 3.490

6.  Effects of DNA methylation on specific transcription by RNA polymerase II in vitro.

Authors:  P L Molloy
Journal:  Mol Biol Rep       Date:  1986       Impact factor: 2.316

7.  Promoter analysis of the PHO81 gene encoding a 134 kDa protein bearing ankyrin repeats in the phosphatase regulon of Saccharomyces cerevisiae.

Authors:  N Ogawa; K Noguchi; Y Yamashita; T Yasuhara; N Hayashi; K Yoshida; Y Oshima
Journal:  Mol Gen Genet       Date:  1993-04

8.  Relationships between a hyper-rec mutation (REM1) and other recombination and repair genes in yeast.

Authors:  R E Malone; M F Hoekstra
Journal:  Genetics       Date:  1984-05       Impact factor: 4.562

9.  Generation of a strong mutator phenotype in yeast by imbalanced base excision repair.

Authors:  B J Glassner; L J Rasmussen; M T Najarian; L M Posnick; L D Samson
Journal:  Proc Natl Acad Sci U S A       Date:  1998-08-18       Impact factor: 11.205

10.  Induced mutagenesis in dam- mutants of Escherichia coli: a role for 6-methyladenine residues in mutation avoidance.

Authors:  B Glickman; P van den Elsen; M Radman
Journal:  Mol Gen Genet       Date:  1978-07-25
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