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Literature DB >> 355857

Induced mutagenesis in dam- mutants of Escherichia coli: a role for 6-methyladenine residues in mutation avoidance.

Abstract

E. coli strains carrying the dam-3 and dam-4 mutations resulting in reduced levels of 6-methyladenine in the DNA have been found to be more sensitive to base analogue mutagenesis than dam+ strains. Mutagenesis by EMS was also found to be enhanced in dam- strains. Dam- mutants however were not found to be hypermutable by UV light. It is concluded that the dam- strains are deficient in the correct repair of mispairing lesions. The data are consistent with the hypothesis that 6-methyladenine residues in the DNA are involved in strand discrimination during mismatch correction.

Entities: Chemical Species

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Year: 1978 PMID： 355857 DOI： 10.1007/bf00271960

Source DB: PubMed Journal: Mol Gen Genet ISSN： 0026-8925

25 in total

1. Mismatch repair in heteroduplex DNA.

Authors: J Wildenberg; M Meselson
Journal: Proc Natl Acad Sci U S A Date: 1975-06 Impact factor: 11.205

2. THE ANALYSIS OF GENETIC RECOMBINATION ON THE POLARON HYBRID DNA MODEL.

Authors: H L WHITEHOUSE; P J HASTINGS
Journal: Genet Res Date: 1965-02 Impact factor: 1.588

3. Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid.

Authors: J D WATSON; F H CRICK
Journal: Nature Date: 1953-04-25 Impact factor: 49.962

4. Repair tracts in mismatched DNA heteroduplexes.

Authors: R Wagner; M Meselson
Journal: Proc Natl Acad Sci U S A Date: 1976-11 Impact factor: 11.205

5. Temporal genetic mapping in the blue-green alga Anacystis nidulans using ethyl methanesulphonate.

Authors: S F Delaney; N G Carr
Journal: J Gen Microbiol Date: 1975-06

6. Complementary specificity of restriction endonucleases of Diplococcus pneumoniae with respect to DNA methylation.

Authors: S Lacks; B Greenberg
Journal: J Mol Biol Date: 1977-07 Impact factor: 5.469

7. Complementary base pairing and the origin of substitution mutations.

Authors: M D Topal; J R Fresco
Journal: Nature Date: 1976-09-23 Impact factor: 49.962

8. Asymmetric information transfer during phi X174 DNA replication.

Authors: P D Baas; H S Jansz
Journal: J Mol Biol Date: 1972-02-14 Impact factor: 5.469

9. Enzymatic synthesis of deoxyribonucleic acid. 36. A proofreading function for the 3' leads to 5' exonuclease activity in deoxyribonucleic acid polymerases.

Authors: D Brutlag; A Kornberg
Journal: J Biol Chem Date: 1972-01-10 Impact factor: 5.157

Review 10. Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli.

Authors: E M Witkin
Journal: Bacteriol Rev Date: 1976-12

78 in total

1. DNA adenine methylase is essential for viability and plays a role in the pathogenesis of Yersinia pseudotuberculosis and Vibrio cholerae.

Authors: S M Julio; D M Heithoff; D Provenzano; K E Klose; R L Sinsheimer; D A Low; M J Mahan
Journal: Infect Immun Date: 2001-12 Impact factor: 3.441

2. Exploring Synergy between Classic Mutagens and Antibiotics To Examine Mechanisms of Synergy and Antibiotic Action.

Authors: Lisa Yun Song; Sara D'Souza; Karen Lam; Tina Manzhu Kang; Pamela Yeh; Jeffrey H Miller
Journal: Antimicrob Agents Chemother Date: 2015-12-28 Impact factor: 5.191

3. Methyl-directed repair of frameshift heteroduplexes in cell extracts from Escherichia coli.

Authors: B A Learn; R H Grafstrom
Journal: J Bacteriol Date: 1989-12 Impact factor: 3.490

4. Differential methylation of chloroplast DNA regulates maternal inheritance in a methylated mutant of Chlamydomonas.

Authors: R Sager; C Grabowy
Journal: Proc Natl Acad Sci U S A Date: 1983-05 Impact factor: 11.205

5. Methylation of chloroplast DNAs in the life cycle of Chlamydomonas.

Authors: H D Royer; R Sager
Journal: Proc Natl Acad Sci U S A Date: 1979-11 Impact factor: 11.205

6. Altered Ca(2+) regulation of Yop secretion in Yersinia enterocolitica after DNA adenine methyltransferase overproduction is mediated by Clp-dependent degradation of LcrG.

Authors: Stefan Fälker; M Alexander Schmidt; Gerhard Heusipp
Journal: J Bacteriol Date: 2006-10 Impact factor: 3.490

7. Use of Drosophila deoxynucleoside kinase to study mechanism of toxicity and mutagenicity of deoxycytidine analogs in Escherichia coli.

Authors: Brittany Betham; Sophia Shalhout; Victor E Marquez; Ashok S Bhagwat
Journal: DNA Repair (Amst) Date: 2009-12-11