OBJECTIVES: To perform a preliminary clinical investigation to determine the safety and efficacy of a novel artificial urinary sphincter (AUS) with conditional occlusion for the treatment of stress urinary incontinence. METHODS: Male patients with urodynamically proven stress urinary incontinence after a prostatectomy were implanted with the novel AUS. They were followed up over a period of 12 months and the device tested for efficacy by using objective measurements of urinary leakage and continence. We derived a new measure for continence called the Continence Index. RESULTS: We have demonstrated that the patients receiving the new AUS showed a reduction of greater than 10-fold in mean daily leakage volume from 770.6 ml to 55.1 ml. There was an overall improvement in the Continence Index from 54% to 97%. CONCLUSIONS: The new AUS with conditional occlusion provides good continence rates and enables adjustment of regulating pressure in situ.
OBJECTIVES: To perform a preliminary clinical investigation to determine the safety and efficacy of a novel artificial urinary sphincter (AUS) with conditional occlusion for the treatment of stress urinary incontinence. METHODS: Male patients with urodynamically proven stress urinary incontinence after a prostatectomy were implanted with the novel AUS. They were followed up over a period of 12 months and the device tested for efficacy by using objective measurements of urinary leakage and continence. We derived a new measure for continence called the Continence Index. RESULTS: We have demonstrated that the patients receiving the new AUS showed a reduction of greater than 10-fold in mean daily leakage volume from 770.6 ml to 55.1 ml. There was an overall improvement in the Continence Index from 54% to 97%. CONCLUSIONS: The new AUS with conditional occlusion provides good continence rates and enables adjustment of regulating pressure in situ.
Authors: Alexander Kretschmer; Alexander Buchner; Markus Grabbert; Christian G Stief; Micaela Pavlicek; Ricarda M Bauer Journal: World J Urol Date: 2015-08-08 Impact factor: 4.226
Authors: Alexander Kretschmer; Tanja Hüsch; Frauke Thomsen; Dominik Kronlachner; Tobias Pottek; Alice Obaje; Ralf Anding; Achim Rose; Roberto Olianas; Alexander Friedl; Wilhelm Hübner; Roland Homberg; Jesco Pfitzenmaier; Ulrich Grein; Fabian Queissert; Carsten M Naumann; Josef Schweiger; Carola Wotzka; Joanne N Nyarangi-Dix; Torben Hofmann; Alexander Buchner; Axel Haferkamp; Ricarda M Bauer Journal: World J Urol Date: 2016-02-25 Impact factor: 4.226